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GlossaryEnzalutamide

blocks male hormones to treat prostate cancer

Enzalutamide, also known by the brand name Xtandi, is a medication used to treat prostate cancer. It works by blocking the action of androgens (male hormones) that can promote the growth of cancer cells. This drug is particularly used in cases where the cancer has spread to other parts of the body and is resistant to other treatments.

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community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 2 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community [Research] RU-58841/Pyrilutamide and impacts on male fertility

in Research/Science 6 upvotes 1 year ago

The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.

community Adrogens and Covid-19

in Treatment 8 upvotes 4 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

community FOR PYRILUTAMIDE NON-BELIEVERS (progress album, 14 months)

in Progress Pictures 30 upvotes 11 months ago

A user shared their 14-month progress using Pyrilutamide and Minoxidil for hair loss, noting improvement and no side effects with these treatments, unlike their negative experiences with Finasteride and RU58841. They emphasized the importance of consistent application for seeing results.

community hair loss treatment alternatives and ideas to improve gain

in Treatment 3 upvotes 1 year ago

The post discusses using finasteride, minoxidil, ketoconazole, and a dermaroller for hair loss, along with spearmint capsules, pueraria mirifica, saw palmetto, biotin, and vitamins. The user is also considering microdosing finasteride with trans treatment and mentions the potential of herbal enemas and hair systems.

community Is Pyrilutamide the real deal and if so when will it actually be available?

in Chat 21 upvotes 2 years ago

Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

community Starting Fluridil (Eucapil) Topical

in Update 12 upvotes 2 years ago

AltruisticBro's experience with Fluridil (Eucapil) as a hair loss treatment, and the current blood work results associated with it. They are not willing to take finasteride due to potential permanent side effects.

community Anyone wanna try and interview the developers of RU?

in Research/Science 82 upvotes 3 years ago

The conversation discusses arranging an interview with the developers of RU58841 to clarify its safety and reasons for halted research, with some users expressing concerns about potential risks and others citing financial reasons for the discontinuation of studies. Specific treatments mentioned include RU58841, minoxidil, and finasteride.

community Currently participating in the Extended Phase III clinical trial of Pyrilutamid in China

in Technology 81 upvotes 1 year ago

A user from China is participating in a clinical trial for Pyrilutamid, a potential hair loss treatment originally developed for prostate cancer. They've experienced no side effects except initial scalp itchiness, and will share results after the year-long trial.

community Kintor Pharma Announces Successful Completion of Phase II Clinical Trial of KX-826 for Treatment of Androgenetic Alopecia in the US

in Research/Science 120 upvotes 1 year ago

Kintor Pharma announced successful Phase II trial results for KX-826 in treating hair loss, showing it's comparable to finasteride and can be used with it. Some participants saw a 10 hair/cm^2 increase, which is considered a good outcome at the low dose used.

community Why you should use 0.5mg Dut instead of 1mg Fin

in Finasteride/Dutasteride 45 upvotes 2 years ago

The comparison of 0.5mg dutasteride and 1mg finasteride for treating hair loss in men with androgenetic alopecia, with discussion of which is more effective and has fewer side effects.

community Using Antihypertensive drugs for hair loss

in Chat 6 upvotes 2 years ago

The conversation discusses the potential connection between baldness, heart disease, and high blood pressure. Treatments mentioned include Minoxidil, Spironolactone, and Finasteride.

community Anyone else crying themselves to sleep because of the pyrilutamide fail?

in Technology 43 upvotes 11 months ago

The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.

community NW4 -> NW 2.5 (2.5 months progress) RU 8.5-9% ED and topical Dut .1% + RU 5% once a week.

in Progress Pictures 108 upvotes 1 year ago

User shows hair loss progress from NW4 to NW2.5 in 2.5 months using RU 8.5-9% daily and topical Dut .1% + RU 5% weekly. Discussion includes managing tension in African American hair and representation of different hair types.

community I'll defeat the norwood reaper with kitchen sink light

in Treatment 26 upvotes 2 years ago

A user who is using a combination of oral and topical treatments, including finasteride, minoxidil, pyrilutamide, dutasteride, microneedling, and ketoconazole shampoo in order to combat hair loss. Another user gave the original poster a word of warning about overusing the ketoconazole shampoo.

community I'm a tressless woman who's ready to call it quits.

in Female 13 upvotes 5 years ago

A woman who is considering giving up on her hair loss journey after trying minoxidil and spironolactone, but other posters offer words of encouragement and suggest the use of wigs.

community First patient dosed with Pyrilutamide (Kintor) Phase III

in Research/Science 201 upvotes 2 years ago

First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.