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GlossaryEndocrine Disruptors (EDCs)

substances that interfere with hormone regulation in the body

Endocrine Disruptors, also known as Endocrine Disrupting Chemicals (EDCs), are substances that can interfere with the endocrine system, which regulates hormones in the body. These chemicals can mimic, block, or alter hormone signals, potentially leading to a variety of health issues such as reproductive disorders, developmental problems, and even certain cancers. They are found in many everyday products, including plastics, pesticides, and personal care items.

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research Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors

103 citations , October 2003 in “Birth Defects Research”

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

research Regulation of Masculinization: Androgen Signaling for External Genitalia Development

45 citations , April 2018 in “Nature Reviews Urology”

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

research Significant Effects of Mild Endogenous Hormonal Changes in Humans: Considerations for Low-Dose Testing

30 citations , March 2001 in “Environmental Health Perspectives”

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

research The Profile of Steroid Hormones in Human Fetal and Adult Ovaries

11 citations , May 2024 in “Reproductive Biology and Endocrinology”

Fetal ovaries produce different hormones than adult ovaries, and endocrine-disrupting chemicals may affect this process.

research Environmental Endocrine Disrupting Chemicals and Their Epigenetic Influence on Androgenetic Alopecia

March 2012 in “Hair transplant forum international”

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

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