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A New Mutation Resulting in the Truncation of the TRAF6-Interacting Domain of XEDAR: A Possible Novel Cause of Hypohidrotic Ectodermal Dysplasia

research A New Mutation Resulting in the Truncation of the TRAF6-Interacting Domain of XEDAR: A Possible Novel Cause of Hypohidrotic Ectodermal Dysplasia

17 citations , August 2012 in “Journal of Medical Genetics”

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

research XEDAR Activates the Non-Canonical NF-κB Pathway

18 citations , August 2015 in “Biochemical and Biophysical Research Communications”

XEDAR triggers a specific signaling pathway in cells.

research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases

6 citations , August 2022 in “International Journal of Molecular Sciences”

EDA signaling is linked to skin disorders, various cancers, and liver disease.

research Epidermal Patterning and Induction of Different Hair Types During Mouse Embryonic Development

81 citations , September 2009 in “Birth defects research”

Different body areas in mice produce different hair types due to interactions between skin layers.

research Molecular Basis of Hypohidrotic Ectodermal Dysplasia: An Update

85 citations , August 2015 in “Journal of Applied Genetics”

Mutations in specific genes disrupt development of sweat glands, teeth, hair, skin, and nails in HED.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 43 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community 2.5 mg/ED dut and 1% pyrilutamide, still getting itch?

in Update 1 upvotes 9 months ago

The user switched from finasteride to 2.5 mg dutasteride daily and added 1% pyrilutamide to address persistent scalp itch, but the itch remains. They also use 2% ketoconazole and 2.5% selenium sulfide shampoo for temporary relief.

community u/joaopassos4444 has zero education in endocrinology, human biology or science, it’s incredibly unlikely he good Will Hunting-ed a medical issue that stumped researchers for thousands of years, please stop buying random supplements based on layman speculation and temper your expectations

in Research/Science 69 upvotes 4 years ago

User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.

community I quit Oral Finasterise over a year ago and here's what I've found

in Finasteride/Dutasteride 52 upvotes 3 weeks ago

The user quit oral finasteride over a year ago, experienced improvements in brain fog and erectile dysfunction after quitting smoking and porn, and plans to try dutasteride. Another user shared their experience with finasteride, mentioning panic attacks and anxiety, and managed symptoms through lifestyle changes like meditation and exercise.

community 1 month fin vs 9 months fin results

in Progress Pictures 516 upvotes 2 years ago

User shares 1-month vs 9-month finasteride results for hair loss. Commenters discuss photo angles, hair regrowth, and side effects.

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