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GlossaryEctodysplasin A

regulates development of skin, hair, teeth, and sweat glands

Ectodysplasin A (Eda) is a protein crucial for the development of ectodermal tissues, which include skin, hair, teeth, and sweat glands. Mutations in the EDA gene can lead to ectodermal dysplasias, a group of disorders characterized by abnormalities in these tissues, often resulting in sparse hair, missing teeth, and reduced ability to sweat.

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Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

research Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

4 citations, July 2020 in “Biochemical and Biophysical Research Communications”

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

Increased Expression of Ectodysplasin A2 Receptor EDA2R Is the Most Remarkable and Ubiquitous Aging-Related Transcriptional Hallmark

research Increased Expression of Ectodysplasin A2 Receptor EDA2R Is the Most Remarkable and Ubiquitous Aging-Related Transcriptional Hallmark

3 citations, August 2021 in “Research Square (Research Square)”

The most common sign of aging at the gene level is more Ectodysplasin A2 Receptor (EDA2R) being made.

research P53-Dependent Transcriptional Regulation of EDA2R and Its Involvement in Chemotherapy-Induced Hair Loss

37 citations, April 2010 in “FEBS Letters”

The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.

research Genetic and Molecular Aspects of Androgenetic Alopecia

24 citations, January 2018 in “Indian Journal of Dermatology, Venereology and Leprology”

Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.

research Genetics of Alopecia

April 2012 in “Encyclopedia of Life Sciences”

Different genes are linked to various types of hair loss.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.