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    Glossary Ectodysplasin A

    regulates development of skin, hair, teeth, and sweat glands

    Ectodysplasin A (Eda) is a protein crucial for the development of ectodermal tissues, which include skin, hair, teeth, and sweat glands. Mutations in the EDA gene can lead to ectodermal dysplasias, a group of disorders characterized by abnormalities in these tissues, often resulting in sparse hair, missing teeth, and reduced ability to sweat.

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    Research 10 of 320

    1. Stimulation of ectodermal organ development by Ectodysplasin-A1 Developmental Biology · 2003 · 249 citations
    2. Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes Developmental biology · 2008 · 117 citations
    3. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011 · 60 citations
    4. Feather arrays are patterned by interacting signalling and cell density waves PLoS Biology · 2019 · 133 citations
    5. Genetics of Alopecia Encyclopedia of Life Sciences · 2012
    6. Molecular cloning,sequence analysis and expression of goat Edagene Journal of Northwest A & F University · 2012
    7. Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness Human Genetics · 2009 · 42 citations
    8. Significant Correction of Disease after Postnatal Administration of Recombinant Ectodysplasin A in Canine X-Linked Ectodermal Dysplasia American Journal of Human Genetics · 2007 · 109 citations
    9. Ectodysplasin-A2 induces dickkopf 1 expression in human balding dermal papilla cells overexpressing the ectodysplasin A2 receptor Biochemical and Biophysical Research Communications · 2020 · 4 citations
    10. A Tale of Two Haplotypes: The EDA2R/AR Intergenic Region is the Most Divergent Genomic Segment between Africans and East Asians in the Human Genome Human Biology · 2012 · 4 citations
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