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GlossaryEctodysplasin A2 Receptor

regulates development of skin, hair, and ectodermal tissues

The Ectodysplasin A2 Receptor (EDA2R) is a protein found on the surface of certain cells that plays a crucial role in the development of skin, hair, and other ectodermal tissues. Mutations in the gene encoding this receptor can lead to conditions like ectodermal dysplasia, which can result in abnormalities in hair growth, skin texture, and dental development.

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research A Review of Genetic Research on Androgenic Alopecia

December 2016 in “Int J Genet”

Male pattern baldness is partly caused by specific genes, but most genetic factors are still unknown.

research Genetic and Molecular Aspects of Androgenetic Alopecia

24 citations, January 2018 in “Indian Journal of Dermatology, Venereology and Leprology”

Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.

Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

research Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

4 citations, July 2020 in “Biochemical and Biophysical Research Communications”

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

research The Biology of Hair Diversity

47 citations, January 2013 in “International Journal of Cosmetic Science”

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

research Evidence for Two Independent Functional Variants for Androgenetic Alopecia Around the Androgen Receptor Gene

26 citations, November 2010 in “Experimental Dermatology”

Two gene areas linked to male pattern baldness found, more research needed.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.