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In this study, researchers found that hair follicle-derived mesenchymal stem cells, modified to overexpress extracellular matrix protein 1, significantly improved liver function and reduced liver damage in cirrhotic mice by inhibiting hepatic stellate cell activation and TGF-β/Smad signaling.

This study observed that extracellular matrix scaffold membranes performed less effectively in wound healing for aged mice compared to younger ones, with senescent SPP1+ macrophages potentially hindering epidermal and fibroblast repair abilities.

This study identified several DPC-specific proteins, including ITGB1, IGFBP3, and THBS1, as potential biomarkers for hair growth modulation through proteomic and network analysis.

In this case report, the researchers identified pathogenic compound heterozygous mutations in a young girl with lipoid proteinosis, noting her relatively mild symptoms and recommending genetic testing for early diagnosis and management of this rare condition.

In this study, around 1% of proteins in skin fibroblasts significantly changed in response to reductive stress, affecting collagens and MAPK signaling pathways.