18 citations
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June 2014 in “Anais Brasileiros de Dermatologia” Clouston Syndrome can be linked to rare sweat gland tumors.
A 72-year-old man was diagnosed with a rare skin form of Rosai-Dorfman disease after years of misdiagnosis.
1 citations
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January 1995 in “Skin Cancer” Immunohistochemistry helps accurately identify and differentiate malignant trichilemmoma.
November 2025 in “Indian Dermatology Online Journal” A 20-year-old male with Clouston syndrome, characterized by alopecia, nail dystrophy, and palmoplantar keratoderma, developed cutaneous squamous cell carcinoma (SCC) on his right great toe. Despite treatment for chronic paronychia, the condition persisted, leading to the discovery of SCC, which was surgically treated with toe amputation. This case is notable as the first reported instance of Clouston syndrome presenting with cutaneous SCC, emphasizing the importance of monitoring for SCC in patients with chronic paronychia and Clouston syndrome. The patient's family history revealed similar symptoms in multiple relatives, indicating a hereditary pattern.
August 2020 in “International Journal of Research in Dermatology” Clouston's syndrome is a rare disorder affecting nails, hair, teeth, and skin, caused by a gene mutation, and currently has no treatment, only supportive care.