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      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

      learn Sulforaphane

      compound from cruciferous vegetables has some mild effects on DHT

    Research

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      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  10 upvotes 5 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

      community Whats the verdict on exosomes?

      in Is this regrowth?  3 upvotes 8 months ago
      The user started finasteride and oral minoxidil for early-stage hair loss around the crown and underwent a session of exosome treatment 3.5 months ago. They are seeing some improvements and are questioning the effectiveness of exosomes for hair regrowth.

      community 1 year on Finasteride, 2 months on derma rolling and minoxidil

      in Progress Pictures  75 upvotes 11 months ago
      The user has been on Finasteride for over a year and recently added minoxidil and derma rolling to their regimen, experiencing side effects like headaches and acne for a few weeks. They tried various non-medication treatments for early-stage hair loss with no success before turning to medication, which improved their hair and confidence.

      community Any long term diffuse thinners success stories?

      in Chat  27 upvotes 1 year ago
      A user with early-stage diffuse hair thinning asked for long-term success stories using treatments like finasteride, minoxidil, and RU58841. One person regained most of their hair after 22 months on finasteride and minoxidil, while another saw significant improvement with oral minoxidil after trying various treatments over many years.