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      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 3 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 3 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community I talked to urologist about Finasteride and just wanted to share what he said

      in Finasteride  235 upvotes 6 years ago
      The effects of Finasteride, a drug used to treat hair loss, prostate problems and other conditions. The post by iaskedadoctor describes the conversations they had with a Urologist about the effects of the drug on DHT levels throughout the body, how lower doses are beneficial in reducing side effects, how erectile dysfunction can be psychological as well as physiological, how morning erections are not necessarily important, and how persistent side effects appear to be rare. People also shared their experiences with taking Finasteride for hair loss, including potential side effects such as reduced ejaculate force and development of man boobs.