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research Application of 3D Bioprinting Technology for Tissue Regeneration, Drug Evaluation, and Drug Delivery

2 citations , January 2023 in “Applied Science and Convergence Technology”

This review discusses the potential of 3D bioprinting technologies for tissue regeneration, drug evaluation, and drug delivery systems, but reports no new findings.

research Novel tip-loaded dissolving and implantable microneedle array patches for sustained release of finasteride

23 citations , July 2021 in “International Journal of Pharmaceutics”

This study describes the development of microneedle array patches for finasteride that released the drug over 7 to 14 days in vitro, suggesting a potential alternative to oral treatments for long-term management of benign prostatic hyperplasia and androgenic alopecia.

research Qualitative study for finasteride detection in the prostate delivered by reversible inhibition of sperm under guidance – Prostate hair (RISUG-PH^™) vas injectable implant

April 2025 in “Journal of Reproductive Healthcare and Medicine”

This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.

research Biocompatibility of KAPs-Depleted Residual Hair

May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that hair with lower levels of keratin associated proteins reduced the foreign body response in mouse subcutaneous implant tests compared to hair with higher keratin levels.

research Biomaterials for Treatment of Baldness

November 2022 in “Cureus”

This study reviews various treatment options for androgenic alopecia, emphasizing the potential use of drug-loaded nanoparticles, but reports no new research results.

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community How far are we from gene editing stem cells and implanting them?

in Research/Science 14 upvotes 6 months ago

Gene editing for hair loss is not yet viable due to technological and economic challenges. Current treatments like Minoxidil, finasteride, and hair transplants remain the most practical options.

community Thoughts on STEM cell hair transplants?

in Transplants 4 upvotes 3 years ago

Stem cell hair transplants are not FDA approved and remain theoretical, with concerns about effectiveness and safety. Current treatments like finasteride and minoxidil are still the main options, while hair cloning and new drug cures are likely years away.

community The Placebo Group Has It Worse Than The Standard Prescription 0.5mg Group. -The fear is all in your head.

190 upvotes 11 months ago

Dutasteride at 0.5mg may have fewer sexual side effects than expected, with many side effects attributed to psychological factors (nocebo effect). The placebo group experienced more side effects, suggesting fear and anxiety might contribute to perceived side effects.

community Am I missing something with pp405?

34 upvotes 1 year ago

PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

community My Delusional Hope - This page becomes irrelevant in 2030s

54 upvotes 10 months ago

People are hopeful for a permanent hair loss solution by the 2030s, considering options like hair cloning and treatments like pp405. Synthetic hair transplants have been attempted but are not effective long-term.

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Learn

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learn Baricitinib

Baricitinib: How did a drug for arthritis end up helping people regrow hair from alopecia areata? Baricitinib, an arthritis drug, was FDA-approved in 2022 for adults with severe alopecia areata after trials in which about a third of patients on 4 mg regained most scalp hair. It carries an FDA boxed warning, and regrowth is usually lost when it is stopped.

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