Search

for
Search:

GlossaryDifferentially Methylated Regions (DMRs)

areas of DNA with varying methylation patterns between samples

Differentially Methylated Regions (DMRs) are specific areas of DNA where the pattern of methylation—a chemical modification that can regulate gene expression—differs between two or more samples, such as between healthy and diseased tissues. These regions are important in studying conditions like alopecia, as changes in methylation can influence the activity of genes involved in hair growth and loss.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 17 results

research Whole-Genome Bisulfite Sequencing of Goat Skins Identifies Signatures Associated with Hair Cycling

28 citations, August 2018 in “BMC genomics”

DNA methylation changes are linked to hair growth cycles in goats.

research Analysis of Genome DNA Methylation at Inherited Coat Color Dilutions of Rex Rabbits

7 citations, January 2021 in “Frontiers in genetics”

Inherited color dilution in rabbits is linked to DNA methylation changes.

research Stepwise Acquisition of Unique Epigenetic Signatures During Differentiation of Tissue Treg Cells

1 citations, December 2022 in “Frontiers in Immunology”

Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

research Analysis of Genome DNA Methylation at Inherited Coat-Color Dilutions of Rex Rabbits

1 citations, January 2020 in “Research Square (Research Square)”

Inherited color dilution in Rex rabbits is linked to DNA methylation changes in hair follicles.

H3K9me3 Methyltransferase SETDB1 Controls Retrotransposon Silencing, DNA Methylation, Constitutive Heterochromatin Maintenance and 3D-Chromatin Structure in Epidermal Keratinocytes

research H3K9me3 Methyltransferase SETDB1 Controls Retrotransposon Silencing, DNA Methylation, Constitutive Heterochromatin Maintenance and 3D-Chromatin Structure in Epidermal Keratinocytes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

View more "dmrs" in research →

Community Join

0 / 0 results

— no results