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GlossaryDisulfide Bonds

strong covalent links between sulfur atoms in proteins

Disulfide bonds, also known as S-S bonds, are strong covalent bonds formed between two sulfur atoms, typically within the amino acid cysteine. These bonds play a crucial role in stabilizing the three-dimensional structure of proteins, including keratin in hair, by linking different parts of the protein chain. In hair, disulfide bonds contribute to its strength and elasticity, and their alteration can affect hair texture and resilience.

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research A Detailed Mapping of the Readily Accessible Disulfide Bonds in the Cortex of Wool Fibers

6 citations , February 2021 in “Proteins”

Researchers found that the most reachable bonds in wool fibers are near the ends of certain proteins, which help stabilize the fiber's structure.

research A Chemist's View of the Analysis of Human Hair for Trace Elements

109 citations , January 1980 in “Science of the total environment”

Analyzing trace elements in human hair is complex and needs a standardized method.

research Structural Change of Keratin Protein in Human Hair by Permanent Waving Treatment

70 citations , June 1998 in “Polymer”

Permanent waving damages hair by disrupting its keratin structure.

research Wanted, Dead and Alive: Why a Multidisciplinary Approach Is Needed to Unlock Hair Treatment Potential

21 citations , February 2019 in “Experimental Dermatology”

Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.

research Key Locations of Oxidative Damage in Human Hair Keratins After Heat and Ultraviolet Light Exposure

September 2025 in “International Journal of Cosmetic Science”

Heat and UV exposure damage hair structure by altering keratins.

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