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GlossaryThioglycolic Acid

chemical used in hair treatments to break disulfide bonds

Thioglycolic Acid, also known as TGA, is a chemical compound commonly used in hair care products, particularly in hair perming and straightening treatments. It works by breaking the disulfide bonds in hair proteins, allowing the hair to be reshaped. This compound is also used in depilatory creams to remove unwanted hair by weakening the hair structure.

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research Action of Thioglycolic Acid and L-Cysteine on Disulfide Cross-Links in Hair Fibers During Permanent Waving Treatment

18 citations, January 2008 in “Sen'i Gakkaishi”

Thioglycolic acid and L-cysteine change hair structure differently during perms, affecting hair strength and curling efficiency.

research Chemical Reactions in Curing Treatment for Permanent Hair Straightening Using Thioglycolic and Dithioglycolic Acids

3 citations, January 2009 in “Sen'i Gakkaishi”

Using both TGA and DTDG in hair straightening reduces hair damage compared to using TGA alone.

research Reproduction Mechanism of Disulfide Cross-Links in Permed Hair by Washing After Reduction with Thioglycolic Acid

2 citations, January 2015 in “Sen'i Gakkaishi”

Washing permed hair after using thioglycolic acid helps reform strong bonds, making hair stronger.

research Intermolecular Disulfide Cross-Linked Structural Change Induced by Permanent Wave Treatment of Human Hair with Thioglycolic Acid

1 citations, December 2012 in “PubMed”

Permanent wave treatment with thioglycolic acid changes hair structure by altering disulfide bonds.

research Assessment on the Effects of Liposome-Encapsulated Thioglycolic Acid on Hair Perming

January 2014 in “Sen i Gakkaishi”

Liposome-encapsulated thioglycolic acid improves hair perming effectiveness and durability.

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