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Research

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research Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis

7 citations , September 2006 in “Molecular Carcinogenesis”

This study observed that K5Cre +/+ transgenic mice develop a distinct phenotype characterized by wavy hair, curly whiskers, and an increased rate of papilloma malignant transformation.

research Trichothiodystrophy: an ultrastructural study of the hair follicle

42 citations , September 1985 in “British Journal of Dermatology”

This study found that trichothiodystrophic hair shows reduced and disoriented protein deposition in follicles, with both the cuticle and cortex affected, providing localized structural insights into keratin abnormalities.

research 177 The Striatin-Interacting Phosphatase And Kinases complex is important for skin epidermal differentiation and barrier formation

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that STRIP1 and the STRIPAK complex play a key role in regulating F-actin and cell-cell junctions, which are essential for maintaining the epidermal barrier in mouse skin.

research Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development

25 citations , September 2018 in “Molecular Biology of the Cell”

This study found that in mice lacking EGFR, elevated Wnt signaling disrupts hair follicle development by affecting cell proliferation and differentiation, revealing a critical role for EGFR in regulating these processes.

research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables

86 citations , December 2001 in “Experimental dermatology”

This review classifies mutant mice with hair abnormalities into six categories, providing an annotated table that serves as a reference for understanding the molecular controls of hair growth.

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Community Join

5 / 1000+ results

community Told my gf I was considering getting back on finasteride

in Finasteride/Dutasteride 2997 upvotes 1 year ago

A user considered restarting finasteride for hair loss despite past side effects, which worried their girlfriend. Others suggested alternatives like topical treatments or lower doses and emphasized prioritizing well-being and relationship stability.

community Avodart (dut) side effects tracking

in Finasteride/Dutasteride 8 upvotes 3 years ago

User tried various hair loss treatments, now switching to Dut and hair transplant. Experienced side effects and plans to track them.

community Looking to make my own 2-Deoxy-D-ribose. Any science bros can give advice?

7 upvotes 2 years ago

A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoic acid. They seek advice on the best carrier oil for hair growth.

community My hairline is confusing

7 upvotes 10 years ago

A user is experiencing hair loss and has been using Propecia, minoxidil, Regenepure DR, and dermarolling, with recent improvements on the left temple but worsening on the right. Suggestions include checking for vitamin deficiencies, thyroid issues, and considering dutasteride.

community my own receding hairline experience

in General 190 upvotes 2 years ago

The user experienced a receding hairline and tried minoxidil, which may have slowed the process but caused puffy eyes. They are hesitant to use finasteride and suspect oily dandruff might be an aggravator.

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Clinics

6 / 39 results

All 39 clinic results →

Learn

4 / 800 results

learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Trichogen® (foligain)

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Experts

1 / 5 results

SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas