July 2026 in “Dermatology and Therapy” In this study, Brazilian dermatologists reported that patients with alopecia areata, particularly those with severe scalp hair loss, often experience an unmet need for advanced therapies that could improve treatment outcomes beyond the limitations of current options.
June 2022 in “Journal of pharmaceutical research international” This article discusses scalp dermatoscopy and home CI therapy as promising diagnostic and treatment options for alopecia areata but reports no new clinical results.
August 2025 in “Clinical and Experimental Dermatology” This study found that although patients with significant scalp hair loss experienced substantial reductions in Severity of Alopecia Tool scores, few maintained this improvement over time, indicating potential suboptimal effectiveness of current treatments.
November 2024 in “SKIN The Journal of Cutaneous Medicine” In this observational study, researchers examined U.S. and Canadian patients with alopecia areata and found that while comorbid anxiety/depression correlated with increased patient-reported disease severity, other comorbidities like atopic dermatitis and vitiligo showed no statistically significant differences in clinician-reported AA severity or hair involvement.
In this retrospective study of alopecia areata patients across several European countries, researchers observed a notable reduction in SALT scores, but few patients reached or maintained a clinically significant SALT score of ≤20, indicating potentially limited effectiveness of current treatments for extensive hair loss.
