2 citations
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December 2021 in “BMC veterinary research” This study found that long-term use of difluprednate ophthalmic emulsion in dogs can lead to HPA axis suppression and potentially cause iatrogenic hyperadrenocorticism, with localized alopecia suspected due to dermal absorption.
January 2010 in “Chinese Medical Journal of Metallurgical Industry” This study found that leflunomide combined with prednisone showed good efficacy and tolerance in treating lupus nephritis where cyclophosphamide was ineffective or intolerable.
January 2008 in “Zhonghua linchuang mianyi he biantai fanying zazhi” This study found that treatment with Shunyou dispersible tablet and prednisone improved clinical symptoms in patients with lupus nephritis, showing significant benefits over time along with a good safety profile.
1 citations
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June 2025 in “Asian Journal of Medical Sciences” In this study, MMF plus prednisolone was found to induce remission in 81% of patients with proliferative lupus nephritis, with fewer adverse effects such as alopecia and amenorrhea compared to CYC plus prednisolone, despite similar overall remission rates.
80 citations
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January 1995 in “The Nephron journals/Nephron journals” This study concluded that a sequential regimen of prednisolone and cyclophosphamide, followed by low-dose prednisolone and azathioprine, achieved favorable results in most patients with diffuse proliferative and/or membranous lupus nephritis without significant toxicities.