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    GlossaryDickkopf-1

    inhibits hair follicle formation, contributing to hair loss

    Dickkopf-1 (DKK1) is a protein that plays a crucial role in regulating cell signaling pathways, particularly the Wnt signaling pathway, which is important for cell growth and development. In the context of hair biology, DKK1 is known to inhibit hair follicle formation and is associated with conditions like androgenetic alopecia (pattern baldness), where its elevated levels can lead to hair loss.

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 3 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Vitamin C and hair growth PH levels

      in Product  34 upvotes 3 years ago
      The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

      community Dht kills hair, but no one says why?

      in Finasteride/Dutasteride  40 upvotes 3 days ago
      DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.