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community Will dht levels increased by creatine cancel out with finasteride

8 upvotes 1 year ago

Creatine may increase DHT levels, but its impact on hair loss is unclear and not well-studied. Many users report no significant hair loss while using creatine alongside finasteride, though some experience increased shedding.

community Does Creatine Really Increase DHT? My Personal Experiment

115 upvotes 1 year ago

Creatine does not increase DHT levels, but some report hair loss when using it, possibly due to other factors. The effects on hair loss vary individually, with no clear connection established.

community Does creatine increase DHT/cause hair loss?

21 upvotes 3 years ago

Creatine is reported to cause increased hair shedding, but there is no scientific evidence linking it to hair loss. Some users manage hair loss with finasteride and minoxidil or consider stopping creatine if shedding worsens.

community Does creatine raise DHT/ contribute to hairloss or is it purely placebo

2 upvotes 2 months ago

Creatine may cause hair shedding in some individuals, but its impact on DHT and hair loss is debated. Many users report no link between creatine and hair loss, while others notice shedding despite using treatments like finasteride and minoxidil.

community NEW Creatine and DHT/Hairloss Study

9 upvotes 1 year ago

Creatine is believed by some users to cause hair shedding, though a study found no increase in DHT or testosterone levels. Many users shared personal experiences of hair loss after using creatine, while others noted no change, suggesting individual variability.

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Research

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research Pharmacokinetics of a transdermal testosterone cream in healthy postmenopausal women

18 citations , May 2014 in “Menopause”

This study found that a 5-mg daily dose of transdermal testosterone cream in postmenopausal women restored testosterone levels to those typical of premenopausal women.

research Formulation and Evaluation of Herbal Cream for the Management of Androgenetic Alopecia

July 2023 in “International journal of life science and pharma research”

In this study, a herbal hair cream containing extracts from Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum was developed, showing promising in-vitro inhibition of the 5α-reductase enzyme and potential benefits for alopecia treatment.

research Alopecia: managing the basics

July 2015 in “Cambridge University Press eBooks”

The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.

research Clascoterone: a new topical antiandrogen agent.

February 2025 in “Prospects in Pharmaceutical Sciences”

This source reports that clascoterone cream, a topical androgen receptor inhibitor, has shown effectiveness in treating facial acne vulgaris in patients 12 and older, with clinical trials indicating a favorable safety profile compared to systemic treatments, and potential for broader dermatological applications.

Expanding The Therapeutic Versatility Of Clascoterone

research Expanding the therapeutic versatility of clacosterone

October 2023 in “Journal of the American Academy of Dermatology”

This source reports that clascoterone cream has been approved in the U.S. for treating acne vulgaris in patients aged 12 and older, suggesting it works by competing with dihydrotestosterone at androgen receptors to mitigate acne's effects.

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Learn

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learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

learn sh-Polypeptide-7

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Bicalutamide

Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss. The published evidence is retrospective case series and one small pilot study, with no randomized trial; it is a prescription drug that requires liver monitoring and is contraindicated in pregnancy.

learn Exosomes

What does Fluridil do on the scalp, and how does it block the DHT hormone? Fluridil blocks DHT by binding to androgen receptors in hair follicles, preventing hair loss.

learn Metformin

Does metformin help control DHT levels that trigger androgenic alopecia? Metformin has been shown to lower circulating androgens in women with PCOS, but no published study has measured scalp DHT, 5-alpha reductase activity in the follicle, or hair density in anyone taking it — so its effect on pattern hair loss is untested, and it is not a DHT blocker.

learn Vitamin B5

Does Vitamin B5 prevent DHT-related androgenic alopecia? Vitamin B5 does not prevent DHT-related androgenic alopecia.

learn Baicapil

Losing hair from hormonal imbalance? Baicapil might block DHT without messing with your hormones. No published study shows that Baicapil blocks DHT — the only data on the ingredient itself is the manufacturer's own unpublished dossier, and the baicalin research behind the claim is cancer cell-line work in which the effect was explicitly independent of the androgen receptor.

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