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GlossaryDiacylglycerol O-Acyltransferase 1 (DGAT-1)

enzyme that catalyzes the final step in triglyceride synthesis

Diacylglycerol O-Acyltransferase 1 (DGAT1) is an enzyme that plays a crucial role in the body's ability to store fat. It catalyzes the final step in the synthesis of triglycerides, which are the main form of stored energy in fat cells. This enzyme is important for energy metabolism and has been studied for its potential links to obesity and metabolic disorders.

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research MEK and BRAF Inhibitors Augment the Production and Accumulation of Sebum in Hamster Sebocytes

April 2016 in “Journal of Investigative Dermatology”

MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.

research Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging

5 citations, October 2021 in “Frontiers in Cell and Developmental Biology”

Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.

research A Guide to Studying Human Dermal Adipocytes In Situ

21 citations, March 2018 in “Experimental Dermatology”

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

research Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands

36 citations, March 2014 in “Molecular and Cellular Biology”

Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.

research Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function

97 citations, September 2016 in “Reviews in Endocrine and Metabolic Disorders”

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

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