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Research

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research Reflectance confocal miscroscopy and dermoscopy analysis of a case of connective tissue nevi

June 2018 in “Chinese Journal of Dermatology”

This study reported that connective tissue nevi show distinctive dermoscopic and RCM features, with RCM being particularly helpful for diagnosing lesions of less than one year in duration.

research Epidermal Nevi

56 citations , October 2010 in “Pediatric Clinics of North America”

This article discusses various types of epidermal nevi and associated syndromes but presents no new research findings.

research 42761 The elusive BAP1 mutation in pediatric melanocytic tumors

September 2023 in “Journal of the American Academy of Dermatology”

In this study of pediatric melanocytic lesions, researchers at Massachusetts General Hospital observed no concurrent BAP1 loss and BRAFV600E positivity, characteristics of adult BIMT, suggesting that these tumors may develop at a later age rather than in childhood.

research Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome

January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study suggests that typical skin lesions in Carney complex may originate from the pro-melanogenic activity of a specific dermal fibroblast population influenced by PKA signaling.

Signaling by Senescent Melanocytes Hyperactivates Hair Growth

research Signalling by senescent melanocytes hyperactivates hair growth

27 citations , June 2023 in “Nature”

In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.

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Community Join

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community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

44 upvotes 1 year ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community Dermal incision with verteporfin

4 upvotes 9 months ago

Dermal incision with verteporfin is being explored as a potential hair loss treatment by dermatologist Melissa Toyos, with promising before-and-after photos shared on social media. The conversation discusses its potential effectiveness compared to other treatments like Minoxidil, Finasteride, and RU58841.

community Derma told me to quit finastirde

in Finasteride/Dutasteride 276 upvotes 10 months ago

A dermatologist advised stopping finasteride after 3-6 months, but many users disagreed, stating it should be used indefinitely to maintain hair. Users recommended finding a new dermatologist due to the perceived misinformation.

community Derma Harmony Sulfur/salicylic acid soap bar shampoo, it caused major hair loss shedding and oily scalp with acne breakout

2 upvotes 1 year ago

The Derma Harmony Sulfur/Salicylic acid soap bar shampoo caused significant hair shedding, oily scalp, and cystic acne. The user experienced better results with rosemary shampoo.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Experts

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Hair Transplant Surgeon
Dr. Neville Campbell
Littleton, CO, United States

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Dr. Neville Campbell