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Research

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research Re-Evaluating The Role of Demodex Mite in Skin Bio-Balance and

March 2022 in “Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology”

This review examines the potential pathogenicity of Demodex mites in skin disorders, considering systemic factors like immunological imbalance and microbiome changes, but reports no new clinical findings.

research SesZen-Bio: A Novel Modulator of Wnt/β-Catenin Signalling for Promoting Hair Growth and Follicular Regeneration

April 2025 in “International Journal of Pharmaceutical Sciences Review and Research”

This study found that SesZen-Bio TM, a proprietary extract from Sesbania grandiflora leaves, increased proliferation of hair cells and hair shaft length in vitro and ex vivo, potentially due to activation of the Wnt/β-catenin signaling and stem cell differentiation pathways.

research Redefining hair restoration with instant results – Is bio-enhanced simultaneous transplant long hair FUE the future?

May 2026 in “Journal of Cutaneous and Aesthetic Surgery”

In this study, researchers developed a novel bio-enhanced hair transplant technique that, among 10 patients, provided aesthetically pleasing outcomes with minimal downtime, linear increases in density over nine months, and uneventful donor area healing with no visible scarring.

research Dermal EZH2 simultaneously orchestrates Wnt/β-catenin signaling dependent dermal differentiation and retinoic acid signaling dependent epidermal proliferation during murine skin development

November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that the Polycomb Repressive Complex 2, particularly its component Ezh2, is crucial in regulating dermal fibroblast differentiation and epidermal keratinocyte proliferation during murine skin development.

research The Role of Immature and Mature Adipocytes in Hair Cycling

30 citations , December 2018 in “Trends in Endocrinology and Metabolism”

The authors concluded that dermal white adipose tissue, influenced by factors like light irradiation, plays a significant role in modulating hair follicle cycles and could be targeted for hair growth treatments.

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Community Join

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community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community On the big 6 but very slow , needs acceleration

in Is this regrowth? 30 upvotes 1 year ago

The user is using a hair regrowth protocol including dutasteride, topical and oral minoxidil, dermarolling, ketoconazole shampoo, and tretinoin, but is experiencing slow progress and seeks advice for faster regrowth. Suggestions include quitting smoking, adjusting the regimen, and considering additional treatments like topical finasteride or RU58841.

community Results after 1.5 year on DUT (progress pictures)

in Progress Pictures 577 upvotes 2 years ago

The user shared impressive hair regrowth results after 1.5 years using dutasteride (DUT) and oral minoxidil. They switched from finasteride and topical minoxidil due to lack of results and experienced no side effects.

community Huberman tweet about finasteride

in Finasteride/Dutasteride 278 upvotes 2 years ago

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

community OND-1 "Cyclosporine A” New hair loss treatment

in Research/Science 28 upvotes 5 months ago

Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

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