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Research

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research Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone

5 citations, January 2017 in “Endocrinology”

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

research Steroidogenesis of the Testis: New Genes and Pathways

70 citations, April 2014 in “Annales d'endocrinologie”

New genes and pathways are important for testosterone production and male sexual development.

research Basics of Androgen Synthesis and Action

35 citations, May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism”

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis

January 2018 in “Elsevier eBooks”

The document explains how male reproductive hormones work and affect the body.

research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation

9 citations, April 2018 in “Biology of reproduction”

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

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Community Join

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community Roughly 1.5 years progress. Dut, Fin, Minox, RU.

in Progress Pictures 802 upvotes 2 years ago

A user's progress with treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, and RU. Other members of the conversation provided tips such as using Microneedling and Tretinoin to increase regrowth and wounding areas of the scalp that are thinning in order to fill them in.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 451 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community Kintor Phase 2 Results released KX-826 (pyrilutamide)

in Research/Science 451 upvotes 2 years ago

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 2 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community Dutasteride Mega Guide – Better Than Finasteride?

in Finasteride 88 upvotes 4 years ago

The potential risks and benefits of using Dutasteride as a hair loss treatment, compared to using Finasteride or other treatments like RU58841 or Accutane. People discussed their personal experiences with these treatments and shared advice on how to proceed.

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