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research Methods for quantifying intrafollicular drug delivery: a critical appraisal

34 citations , July 2010 in “Expert Opinion on Drug Delivery”

This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.

research Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles

4 citations , July 2023 in “Pharmaceutics (Basel)”

This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.

research Effect of oil, water and surfactant mixture on the physicochemical properties and transdermal delivery of finasteride-loaded microemulsions: evaluation and prediction using response surface methodology

January 2017 in “Isan Journal of Pharmaceutical Sciences”

This study explored microemulsion formulations for delivering finasteride through the skin, finding that higher water concentrations increased permeation, which may inform optimal transdermal delivery for treating androgenetic alopecia.

research Physical methods for topical skin drug delivery: concepts and applications

22 citations , November 2018 in “Brazilian Journal of Pharmaceutical Sciences”

This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.

research Transdermal delivery of finasteride invasomes using taguchi robust design method

July 2013 in “Pharmaceutical Regulatory Affairs Open Access”

This study reported that invasomes, utilizing limonene as a component, enhanced the transdermal permeation of finasteride by over 21 times, indicating their potential as a novel drug delivery system.

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5 / 389 results

community Why don't do it yourself topical solutions not talk about ethosomes as delivery mechanism?

4 upvotes 10 months ago

Ethosomes are suggested as an effective delivery method for topical finasteride solutions, requiring the addition of a phospholipid like soya lecithins. The user questions why do-it-yourself solutions don't commonly use ethosomes despite their potential benefits.

community Soundwaves & Electricity Grows Hair? | Peptide Delivery Model.

2 upvotes 2 years ago

Iontophoresis and sonophoresis can enhance drug delivery into the scalp. Combining these methods may improve the effectiveness of topical treatments like dutasteride and certain peptides.

community Has Anyone Heard About Ethossomal Finasteride? 6x Finasteride Delivery in Hair Folicule?

36 upvotes 3 years ago

A user is considering switching from oral to topical finasteride to reduce systemic DHT impact and is exploring ethossomal finasteride for better skin penetration and potential hair regrowth. They found ethossomal finasteride in Brazil and are seeking opinions on its effectiveness compared to other topical delivery methods.

community Experiences with CB-03-01?

5 upvotes 10 years ago

CB-03-01 is considered too costly and lacks a proper delivery method, making it less viable compared to RU58841, which has shown effectiveness with minimal side effects. Finasteride caused a drop in libido for one user.

community Did some new info come out about PP405? Everyone seems so pessimistic about it recently and I don’t know why.

1 upvotes 1 month ago

People are pessimistic about PP405, believed to be Jxl-069, due to doubts about its effectiveness and delivery method. Some think it doesn't work, while others blame the vehicle used for application.

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