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5α-Reductase Inhibitors and Male Reproduction

research 5α-Reductase Inhibitors (5ARIs) and Male Reproduction

15 citations , January 2017 in “Advances in Experimental Medicine and Biology”

This review discusses the effects of 5ARI drugs on male reproductive parameters, reporting potential decreases in sperm count and motility more significantly in men with pre-existing oligozoospermia, but does not provide fertility outcomes.

research A Mutation of the Androgen Receptor Associated with Partial Androgen Resistance, Familial Gynecomastia, and Fertility*

67 citations , April 1988 in “The Journal of Clinical Endocrinology & Metabolism”

This study describes a family with X-linked gynecomastia and undervirilization in men, finding a subtle androgen receptor abnormality that may not always lead to infertility despite androgen resistance.

Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

18 citations , October 2021 in “Frontiers in Physiology”

This review summarizes recent research on the molecular properties and functions of L-PGDS and PGD2, but reports no new findings, highlighting their pathophysiological roles and guiding future studies.

Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms

research Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms

18 citations , June 2009 in “Journal of Molecular Endocrinology”

This study found that exposure to finasteride impaired spermatogenesis in male Xenopus laevis by affecting sex-specific feedback mechanisms in the hypothalamus–pituitary–gonad axis.

research Finasteride use in the male infertility population: effects on semen and hormonal parameters

1 citations , August 2013 in “Fertility and Sterility”

Finasteride may improve sperm count in subfertile men with low sperm count.

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community H as anyone done sperm/fertility test before and after staring finasteride?

6 upvotes 6 years ago

The conversation discusses the impact of finasteride on sperm, including potential side effects like decreased ejaculate volume and total sperm count. Users share experiences and concerns about fertility tests before and after starting finasteride.

community New study compared twice weekly, thrice weekly DUT and daily finasteride

in Research/Science 27 upvotes 9 months ago

Dutasteride is effective for hair loss but may cause side effects like decreased sperm count, which might not fully recover after stopping. Users discuss balancing dosages to minimize side effects while maintaining benefits.

community What do you think about drinking spearmint tea while on finasteride?

3 years ago

The user is concerned that drinking spearmint tea while on finasteride might harm sperm count, mobility, and testosterone levels, despite seeing positive effects on hair. They seek advice on whether to continue or stop the tea.

community Finasteride Watery Semen

3 upvotes 6 years ago

A user noticed watery semen and decreased volume after a week of using finasteride and asked if taking Zinc, pygeum, and lecithin supplements would affect finasteride's effectiveness. The conversation is about the side effects of finasteride and potential supplements to counteract them.

community An Update After 7 Years of Finasterise

in Progress Pictures 126 upvotes 1 year ago

The user shared their positive experience with finasteride for hair loss over seven years, noting it stopped hair recession and maintained their hairline. They also mentioned using minoxidil irregularly and experiencing a lower sperm count but no erectile dysfunction.

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