April 2026 in “Academic Dermatology” In this retrospective observational study, researchers found that the Dean Scale showed better diagnostic accuracy than the CTCAE scale for detecting clinician-reported therapeutic responses to minoxidil in patients with anticancer therapy-induced alopecia, but both scales had limitations in recording clinically significant hair regrowth.
January 2021 in “Mastology” This study found that over 80% of women treated with paclitaxel who used a hypothermic glycerin-based hydrogel cap preserved at least 50% of their initial hair volume, suggesting scalp cooling may effectively prevent chemotherapy-induced alopecia.
November 2018 in “Annals of oncology” This study found that the computer-controlled RV-01 scalp cooling device helped prevent significant hair loss in metastatic breast cancer patients treated with eribulin, with none of the 16 patients requiring a wig and experiencing minimal discomfort.
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June 2017 in “Developmental Biology” This study found that local refinement of hair follicles into higher order patterns can occur without the core planar cell polarity system, but global alignment with body axes requires its function throughout development and regeneration.
November 2007 in “Neuro-chirurgie/Neurochirurgie” This study reported that treatment with cyproterone acetate alone and then with incremental estrogen doses induced mild feminizing effects in late-pubertal trans-girls, with further feminization observed after adding estrogen.