70 citations
,
April 2014 in “Annales d'endocrinologie”
This review discusses the pathways of androgen biosynthesis and reports no new findings, highlighting the need to understand the interplay between the classic and backdoor pathways.
23 citations
,
June 2015 in “Clinica Chimica Acta”
In this study, researchers identified two potential urinary biomarkers, testosterone–glucuronide and 11α-hydroxyprogesterone, along with four candidate biomarkers, to help understand and diagnose polycystic ovary syndrome.
In this study, intrathecal progesterone administration initially worsened mechanical allodynia in mice after nerve injury, but later reduced pain when applied during the maintenance phase, highlighting distinct roles for cytochromeP450c17 and 5α-reductase in neuropathic pain modulation.
49 citations
,
November 2019 in “Egyptian Journal of Medical Human Genetics”
This review discusses the role of CYP gene polymorphisms in exacerbating hyperandrogenism in women with PCOS and reports no clinical results; further validation of this hypothesis is needed.