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Did you mean Cyclooxygenase-2?

GlossaryCyclooxygenase-2

enzyme involved in inflammation and pain production

Cyclooxygenase-2 (COX-2) is an enzyme that plays a crucial role in the inflammatory process by converting arachidonic acid into prostaglandins, which are compounds that mediate inflammation and pain. Unlike its counterpart COX-1, which is expressed constantly in most tissues, COX-2 is typically induced during inflammation and is a target for anti-inflammatory drugs like NSAIDs (nonsteroidal anti-inflammatory drugs).

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Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFkB and AP-1

research Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFkB and AP-1

1 citations, February 2023 in “International Journal of Molecular Sciences”

Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.

research Comprehensive Evaluation of Clinical Efficacy and Safety of Celecoxib Combined with Chemotherapy in Management of Gastric Cancer

18 citations, December 2017 in “Medicine”

Adding celecoxib to chemotherapy improves survival and quality of life for gastric cancer patients with positive COX-2.

research Saw Palmetto and Finasteride in the Treatment of Category-III Prostatitis/Chronic Pelvic Pain Syndrome

5 citations, March 2005 in “Current Urology Reports”

Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.

research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications

1 citations, March 2024 in “Signal transduction and targeted therapy”

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

research Skin Toxicity of Anti-Cancer Therapy

19 citations, October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft”

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

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