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research Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR-Cas9 in the Genetic Improvement of Sheep and Goats

March 2024 in “Agriculture”

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

research Spatiotemporal Control of CRISPR/Cas9 Gene Editing

51 citations , June 2021 in “Signal Transduction and Targeted Therapy”

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies

research Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies

June 2024 in “International Journal of Nanomedicine”

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

research Tailored Chromatin Modulation to Promote Tissue Regeneration

10 citations , May 2019 in “Seminars in Cell & Developmental Biology”

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management

research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management

1 citations , April 2023 in “International Journal of Molecular Sciences”

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

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community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 23 upvotes 4 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community Wet hair progress (4 months 1mg finasteride daily then 8 months .5mg dutasteride every 3rd day) with nizoral 3x per week

in Progress Pictures 203 upvotes 3 years ago

User shared 12-month hair growth progress using finasteride and dutasteride, with nizoral 3x per week. They experienced a finasteride shed but saw improvement after a year and offered advice for managing hair loss expectations.

community 1y 2 mo of 0.5 mg fin daily, minox 5% and nizoral 2%. Just giving back to the community cuz Reddit saved me a year ago. Don’t lose hope, things do work out

in Progress Pictures 55 upvotes 3 years ago

The user's progress with hair loss treatments of 0.5mg finasteride daily, minoxidil 5%, and nizoral 2%. They discuss if further growth is possible, their experience after two months, and encourage others to not lose hope.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 1 month ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community Had a son while being on FIN, MUST READ

in Finasteride/Dutasteride 619 upvotes 2 years ago

A user shared his experience of having two healthy children while continuously using finasteride (Fin) for hair loss, challenging fears about its potential impact on fetal development. The discussion that followed included various perspectives, with some users sharing similar experiences, others expressing concerns about potential risks, and some emphasizing the need for more substantial evidence before drawing conclusions.

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