This study developed a new method using liquid chromatography-tandem mass spectrometry to measure multiple steroid hormones in hair, requiring significantly fewer strands than previous methods, with high accuracy and precision.
This study found that cortisol levels, a biomarker of chronic stress, significantly increased in the post-COVID-19 lockdown period compared to pre-lockdown and during-lockdown periods, especially among females and young adults, reflecting sustained psychological stress from the pandemic.
3 citations
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October 2021 in “Clinica Chimica Acta”
This study found that higher levels of dihydrotestosterone in the parietal region of the scalp may correlate with the clinical presentation of androgenetic alopecia.
What are the risks of long-term hydrocortisone use on the scalp?Dermatology reviews describe long-term topical corticosteroid use as causing skin thinning, delayed healing, greater infection risk, possible suppression of the body's own cortisol, and rebound flares on stopping. US over-the-counter hydrocortisone labels say to stop and ask a doctor if symptoms last more than seven days.
How do you safely apply hydrocortisone cream or lotion to the scalp without overusing it?US over-the-counter hydrocortisone labels say to apply it no more than three or four times a day and to stop and ask a doctor if symptoms last more than seven days; labels in other countries differ. The scalp absorbs corticosteroids more than most skin, so prolonged use raises the risk of thinning skin.
Can hydrocortisone be used together with other treatments like minoxidil or steroid injections?If minoxidil solution irritates the scalp, the cause may be irritation, seborrhoeic dermatitis or an allergy to an ingredient, so it is worth having a doctor or pharmacist look before adding a steroid. No verified trial tests hydrocortisone alongside minoxidil or corticosteroid injections, and prolonged scalp use risks skin thinning.
The user experienced significant hair regrowth over 8 months using finasteride, minoxidil, and a custom topical mix including progesterone, cortisone, and alpha 5 estradiol. They reported no side effects and noticed improvement around the third month.
The user discusses their experience with minoxidil for hair loss, noting that drinking coffee may reduce its effectiveness. They observed better results with the liquid solution and no coffee compared to using the foam solution and drinking coffee.
Minoxidil alone is not effective for significant hair regrowth; combining it with finasteride or dutasteride is necessary. Additional treatments like hair transplants, microneedling, or oral medications are recommended for better results.
A user developed a rash after 3 years of using Kirkland minoxidil foam, possibly due to a change in ingredients. They are considering switching to Foligain or Rogaine foam to avoid further issues.
A 22-year-old male is using a combination of oral Minoxidil, Finasteride, topical solutions, and supplements to combat male pattern baldness, with plans to add RU58841. Some users suggest adding treatments targeting androgen receptors and question the necessity of certain supplements.