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This study developed and validated a comprehensive method using mass spectrometry to profile sex (pro)hormones in plasma, with results showing reliable calibration and detection of 31 analytes in samples from pre- and postmenopausal women and men, while addressing potential over- or underestimations in analyte concentrations.

This study found that in androgenetic alopecia mice, MNX@Arg-CLAVs, a novel nanovesicle platform containing minoxidil and conjugated linoleic acid, enhanced hair regeneration and reduced hair follicle aging more effectively and with less irritation compared to traditional minoxidil tincture.

This study found that MNX@Arg-CLAVs nanovesicles enhanced hair regeneration and reduced aging in hair follicles in AGA mice, with less skin irritation compared to traditional minoxidil tincture.

In this study on mice, researchers developed CLA-loaded nanovesicles that showed potential anti-aging effects on hair follicles and enhanced hair growth compared to commercial minoxidil, with lower skin irritation, suggesting a promising approach for treating androgenetic alopecia.

This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.