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      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

       23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community Loosing ground while on dut 0.5

       5 upvotes 2 weeks ago
      The user switched from finasteride to dutasteride but experienced more hair thinning, questioning whether to switch back. Others shared similar experiences, suggesting patience or considering different dosages, while some noted potential issues with testosterone levels.

      community UPDATE - 7 months 2,5 dutatesteride

       10 upvotes 1 year ago
      The user continues to experience hair loss despite using dutasteride 2.5mg, minoxidil 5mg, and ciclopirox shampoo, and plans to reassess after one year. Others report similar issues with dutasteride, with some switching to finasteride or adding RU58841.

      community Dutesteride time at which maximum serum DHT is supressed?

       5 upvotes 3 years ago
      Maximum serum DHT suppression for finasteride occurs at 8 hours, while for dutasteride, it occurs within 1 to 2 weeks with daily dosing. Dutasteride mesotherapy will be followed by blood tests to check serum DHT changes.

      community A warning to those using or thinking about using Dutasteride – Follow-up

       18 upvotes 5 years ago
      The post and conversation are about the long-term side effects of using Dutasteride and Finasteride for hair loss, including issues like raised liver enzymes, high cholesterol, and loss of libido. The user advises regular blood work and careful monitoring for those using these treatments.

      community Blood work after one year of fin/dut

       7 upvotes 3 years ago
      After using finasteride and dutasteride for hair loss, a user's blood tests showed almost unchanged DHT levels and some out-of-range hormone levels. They experienced side effects when taking dutasteride daily and also take supplements that boost testosterone.

      community thoughts on dutasteride mesotherapy?

       3 upvotes 3 years ago
      Dutasteride mesotherapy for hair loss, with the user reporting minimal pain during the procedure. Other users mention success stories and inquire about additional treatments.

      community High Estrogen and Test on Dut 5x a week

       6 upvotes 1 year ago
      A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

      community 1 year 5-ar. Blood test results

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      The user experienced sexual side effects after starting finasteride and later switched to dutasteride, noticing hormonal changes. They are considering using P5P and possibly aromatase inhibitors to manage high prolactin and estradiol levels.

      community Zero Progress on dutasteride :(

       60 upvotes 5 months ago
      The user is frustrated with minimal hair regrowth after using dutasteride, oral minoxidil, and previously finasteride and topical minoxidil. Despite feeling discouraged, others suggest continuing treatment as progress can be slow and subtle, with some users noting visible improvement.

      community Bloodwork: what to test for?

       6 upvotes 6 years ago
      The user has been taking oral Finasteride and topical Essengen 6 Plus for hair loss and is experiencing increased depression. They plan to get bloodwork to check hormone levels and are seeking advice on which tests to include.

      community How finasteride or DUT works for me

       1 upvotes 6 months ago
      Some users experience side effects from finasteride and switch to alternatives like pyralutamide and a finasteride-minoxidil mix. These alternatives may reduce side effects while helping with hair loss.

      community 2 months Dutasteride - hyperresponder?

      in Progress Pictures  148 upvotes 3 months ago
      OP experienced significant hair growth after switching from topical treatments to oral Dutasteride, alongside using CJC/Ipamorelin and Cialis. They stopped using topical Minoxidil and Finasteride, attributing the hair growth to the new regimen.

      community Dutasteride thrice weekly beats finasteride. But daily?

      in Finasteride/Dutasteride  31 upvotes 9 months ago
      Dutasteride taken three times a week is more effective for hair regrowth than daily finasteride, with fewer side effects. Some users combine dutasteride and finasteride for better results, while others prefer dutasteride alone due to its longer half-life and potential fertility concerns.

      community 6 months of dutasteride + minoxidil.

       114 upvotes 6 months ago
      A 31-year-old male experienced significant hair regrowth after 6 months using daily 0.5 mg dutasteride, 5% topical minoxidil twice a day, occasional dermarolling, and hair supplements. He reported a slight decrease in libido initially but no other side effects, and there's potential for further improvement up to 12–18 months.

      community 28 month update. 0.5 dut daily

      in Progress Pictures  16 upvotes 5 months ago
      A user reversed hair loss using 0.5 mg of dutasteride daily without side effects. Others noted hair thickening but questioned the absence of minoxidil use.

      community 1 month progress - Dutasteride + Minoxidil

      in Progress Pictures  6 upvotes 5 months ago
      A user shared their 1-month progress using Dutasteride and Minoxidil for hair loss, noting some early signs of regrowth but no significant changes yet. They experienced mild impotence as a side effect, which has mostly subsided.

      community Why don’t people just just DUT instead of FIN?

      in Finasteride/Dutasteride  48 upvotes 2 years ago
      The conversation discusses the use of dutasteride (DUT) versus finasteride (FIN) for hair loss treatment, with some users preferring DUT for its effectiveness while others choose FIN due to its approval status, better long-term data, and lower risk of side effects. Users share personal experiences with both medications, including side effects and effectiveness.

      community Dut once a week vs finaster 0.25mg daily? What maintains better?

      in Treatment  5 upvotes 1 month ago
      The user is experiencing increased hair shedding after reducing finasteride to 0.25mg daily and taking dutasteride once a week. They are considering adding KX-826 to their regimen and are seeking advice on whether to increase dutasteride frequency or return to finasteride.

      community 2 years on treatment (stack update)

       465 upvotes 1 year ago
      A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

      community 6 Months Update Dutasteride and Oral Minoxidil 2.5mg Daily

       21 upvotes 2 weeks ago
      The user has been using Dutasteride and Oral Minoxidil 2.5mg daily for 6 months, experiencing improved erections and libido, but feeling less enthusiastic about people. Other users commented on the improvement and discussed hair shedding and alternative treatments.

      community 2 year progress with Dut after a decade of Fin

       154 upvotes 4 months ago
      A user shared their hair loss journey, using finasteride since age 18 and adding dutasteride at 30, which halted hair loss and promoted regrowth. They take finasteride daily and dutasteride three times a week, experiencing reduced libido and drier skin as side effects.

      community On Dutasteride 0.5mg ED for almost 2 years. Increasingly shedding hair for more than 5 months.

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      The user experienced increased hair shedding after switching from finasteride to dutasteride, despite lifestyle improvements and additional treatments like oral minoxidil and PRP. They are concerned about persistent shedding, changes in hormone levels, and potential chronic telogen effluvium, and are considering a scalp biopsy for further investigation.

      community Dutasteride positive stories/experiences

      in Finasteride/Dutasteride  9 upvotes 1 month ago
      Users shared positive experiences with dutasteride for hair regrowth after switching from finasteride, with some noticing improvements in hair growth and stability. Many advised a gradual transition from finasteride to dutasteride for better results.

      community Hormonal changes on Finasteride?

       37 upvotes 1 year ago
      Finasteride can increase estrogen levels, causing dizziness and nausea. Users discuss adjusting treatment and diet, and explore alternatives for hair loss management.