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    GlossaryTransforming Growth Factor Alpha

    protein involved in cell growth and hair follicle regulation

    Transforming Growth Factor Alpha (TGF-α) is a protein that plays a crucial role in cell growth, proliferation, and differentiation. It binds to the epidermal growth factor receptor (EGFR) on the cell surface, triggering a cascade of cellular processes that can influence tissue development and repair. In the context of hair biology, TGF-α is involved in the regulation of hair follicle development and cycling, and its dysregulation can be associated with conditions like alopecia.

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