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GlossaryTransdermal Estrogen

delivers estrogen through the skin via patches or gels

Transdermal Estrogen refers to a method of delivering estrogen through the skin using patches, gels, or creams. This form of hormone replacement therapy is often used to treat symptoms of menopause, such as hot flashes and osteoporosis, by maintaining more consistent hormone levels and potentially reducing the risk of side effects compared to oral estrogen.

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community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 month ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community 4 years; fin 1mg/day @ 4 years; minox twice daily @ 3 years; estradiol 5mg/day @ 3 months; spiro 100 mg /day @ 3 months (Wet hair because it's easy to hide issues with dry hair)

in Progress Pictures 198 upvotes 4 months ago

The user shared their 4-year hair regrowth progress using finasteride, minoxidil, estradiol, and spironolactone. They noted significant regrowth by the second year and additional benefits from estradiol and spironolactone.

community My strong recommendation for those shedding hair

in Treatment 92 upvotes 3 years ago

A user with aggressive male pattern baldness found that topical melatonin significantly reduced their hair shedding to 1 or 2 hairs per day and noticed some thickening of side hair. They tried many treatments like finasteride and minoxidil with little success, but topical melatonin showed immediate results in reducing hair loss.

community Hair Regrowth by Transdermal Dissolvable Microneedles Loaded with Rapamycin and Epigallocatechin Gallate Nanoparticles - PubMed

in Research/Science 15 upvotes 2 years ago

The conversation discusses hair regrowth using dissolvable microneedles loaded with rapamycin and epigallocatechin gallate nanoparticles. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Wanted to share my hairloss treatment. All in one solution. Did a trichotest and they made me this solution. In addition I use caffeine liquid and saw palmento. Been on this for 40days now, started sheding. (Been on minoxidil 5% for a year befor this). What do you guys think?

in Treatment 48 upvotes 2 years ago

A user shared their hair loss treatment which includes a custom solution with multiple ingredients, caffeine liquid, and saw palmetto, and mentioned shedding after 40 days of use. Some replies discuss the effectiveness and cost of the treatment, while others debate the usefulness of topical dutasteride.

community Impressed by the progress but think it’s time to go for the transplant?

in Progress Pictures 288 upvotes 10 months ago

The user started taking 2.5mg minoxidil tablets daily and reduced their finasteride dose to 0.5mg due to side effects. They are considering a hair transplant but are unsure if they should proceed now or wait after seeing the effects of the reduced finasteride dosage.

community Only on topical minoxidil with 0.1% fin and doing dermarolling once a week what you guys think?

in Progress Pictures 418 upvotes 1 year ago

The user "deadstroke56" shared their progress using topical minoxidil with 0.1% finasteride and dermarolling once a week for hair loss. Other users praised their progress and asked about the brand and regimen used.

community Progressive insomnia (treatment-resistant) due to Finasteride

in Finasteride/Dutasteride 7 upvotes 2 years ago

A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 5 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 8 months ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Anything stronger than DUT out there?

in Finasteride/Dutasteride 14 upvotes 9 months ago

The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

community Could microneedling for the next 5 years cause any permanent damage?

in Microneedling 22 upvotes 1 year ago

Microneedling for hair loss and its potential long-term effects. Some users believe it can cause fibrosis and scar tissue if done too frequently or deeply, while others claim it has improved their hair loss when done correctly. There is limited scientific research on the topic.

community 1 year progress on fin and min

in Progress Pictures 94 upvotes 1 year ago

User shared 1-year progress using finasteride and minoxidil for hair loss, with positive results. Another user discussed their own experience, considering switching from topical to oral minoxidil.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 103 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community What are your thoughts on Redensyl? 85% success rate?!

in Treatment 6 upvotes 2 years ago

Hair loss discussion mentions Redensyl with 85% success rate and visible regrowth. Users skeptical, prefer Minoxidil, Finasteride, and RU58841.

community Results of Procyanidin B2 in clinical studies

in Treatment 13 upvotes 4 years ago

Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Homemade Topical Finasteride Formula?

in Treatment 6 upvotes 2 years ago

User wants to make homemade topical finasteride to minimize side effects and asks about using glycerin, stirring time, storage, and alternative solvents. Another user's comment is unclear.

community Topical Valproic acid/sodium valproate — has anyone tried this?

in Question 2 upvotes 4 years ago

The conversation is about using valproic acid, an anti-seizure medication, as a topical treatment to promote hair growth. The original poster is seeking personal experiences from those who have tried this method.

community Just a little update. RU, minox, and Dut

in Progress Pictures 1075 upvotes 2 years ago

User discusses hair regrowth using RU58841, minoxidil, and dutasteride. Many users praise the progress and ask about the treatments' effectiveness and side effects.