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GlossarySystemic Medications

drugs that affect the entire body via bloodstream

Systemic medications are drugs that work throughout the entire body rather than targeting a specific area. They are often taken orally or injected, allowing the active ingredients to enter the bloodstream and reach various tissues and organs. This type of treatment is commonly used for conditions that affect multiple parts of the body, such as autoimmune diseases or widespread infections.

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community 6 months aggressive treatment for hair loss

in Progress Pictures 115 upvotes 8 months ago

The user shared a 6-month aggressive hair loss treatment progress, using oral minoxidil, finasteride/minoxidil topical, dutasteride, derma stamping, Nizoral, and daily Cialis, which notably improved regrowth. Commenters observed significant improvement, with one noting a change from a Norwood 5 to a Norwood 1 in hair loss classification.

community Spain is treating AGA hairloss in 90% cases

in Treatment 15 upvotes 3 years ago

Hair transplants, oral finasteride, oral minoxidil, and dutasteride mesotherapy are highly effective for treating AGA hair loss. This combination can maintain and improve hair for most people, except those with very aggressive AGA.

community M23 on Hims Fin and Min solution for 4 months now progress

in Progress Pictures 149 upvotes 1 year ago

The conclusion of the conversation is that some users have seen positive results with the use of finasteride and minoxidil for hair loss, while others have not. It is mentioned that consistent use of these treatments is necessary to maintain results.

community Oral Biotin and Topical Minoxidil have a synergy effect in increasing hair growth, the study was only done in healthy subjects and it was only 14 days but it does prove that biotin can play a significant role as an adjunct treatment.

in Research/Science 170 upvotes 1 month ago

Oral biotin combined with topical minoxidil may increase hair growth rate, though the study was limited to healthy subjects and did not measure hair density. Some users report personal benefits from biotin, such as faster nail growth and healthier hair, but concerns about acne and study quality were also mentioned.

community Topical Minoxidil is a pain in the ass for diffuse thinners

in Minoxidil 95 upvotes 1 year ago

Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

community Is this enough to regrow my lions mane and if no what am I missing?

in Chat 1 upvotes 6 months ago

A user is trying to regrow hair using a natural approach without Minoxidil or finasteride, focusing on micro-needling, red light therapy, and various oils and serums. Other users suggest that medical treatments are more effective for male pattern baldness.

community Lowering DHT vs measured level and topical scalp treatment issues

in Research/Science 1 upvotes 8 months ago

The conversation discusses the effects of lowering DHT on hair loss and the importance of monitoring DHT levels during treatment. The user suggests that individual responses to DHT and hair loss treatments vary, and expresses a preference for topical treatments over oral medications due to concerns about systemic DHT reduction.

community If apply topical fin goes systemic then does it matter where I apply it on the scalp?

in Finasteride/Dutasteride 10 upvotes 6 months ago

The conversation is about whether topical finasteride and minoxidil need to be applied directly to the affected areas of the scalp or if they can be spread through blood vessels. It also asks how long topical finasteride remains on a pillow.

community Comparison of options: topical vs medication

in Female 1 upvotes 5 months ago

A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

community If Ru58841 was an FDA approved medication and known to be safe would you recommend it before finasteride?

in Product 7 upvotes 11 months ago

The conversation discusses whether RU58841, if FDA approved and safe, would be recommended over finasteride for hair loss. Specific treatments mentioned include RU58841, finasteride, and minoxidil.

community I experimented with every medication for hair loss for at least 1 year. my thoughts.

in Treatment 66 upvotes 2 years ago

Minoxidil effective for regrowth but causes dryness; finasteride stops hair loss but may affect hormones; dutasteride powerful but reduces libido; RU58841 thickens hair but expensive and risky; dermarolling improves blood flow and results; aminexil overrated and not effective. Dermarolling beneficial with both minoxidil and finasteride.

community My experience with beard loss derived from hair loss medication and

in Finasteride/Dutasteride 7 upvotes 3 months ago

The user experienced beard loss from finasteride and RU58841 while managing hair loss. They plan to increase RU58841 dose, use a dermaroller, and consider oral minoxidil to improve hair growth without affecting their beard.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 90 upvotes 4 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community Please listen. If you want to save your hair.

in Progress Pictures 126 upvotes 2 years ago

User discusses two medications for stopping hair loss: Fin (finasteride) and Dut (dutasteride). Mixed experiences and side effects are shared, with some users seeing positive results.

community Antihistamines stop my hair loss

in Treatment 24 upvotes 2 years ago

A user found that antihistamines stop their hair loss and related symptoms, but they experience side effects like sedation and chest pain. They are seeking alternative solutions or topical antihistamines to avoid systemic side effects.

community 8 mos: oral (Du, Min), topical (Min, Ru, Ketoconazole), microneedling. NW7 for 7 years

in Progress Pictures 944 upvotes 1 year ago

A user's success in hair regrowth after taking oral and topical medications, such as minoxidil and dutasteride, and using microneedling. Other users shared their experiences and advice with treatments used to reverse hair loss.

community Topical Valproic acid/sodium valproate — has anyone tried this?

in Question 2 upvotes 4 years ago

The conversation is about using valproic acid, an anti-seizure medication, as a topical treatment to promote hair growth. The original poster is seeking personal experiences from those who have tried this method.

community My nuclear protocol (scary but very effective)

in Treatment 81 upvotes 2 years ago

A hair loss treatment protocol involving topical and oral medications such as Minoxidil, RU58841, Finasteride, Dutasteride, Melatonin, Zinc, Vitamin B6, NAC, Caffeine, Biotin, Ginseng, and Semen; other treatments including Microneedling, Laser Helmet, Nizoral shampoo, Scalp Massage and supplements like Vitamin C, Vitamin D, Fish Oil, and Biotin; and the potential side effects of using this protocol.

community How is there still no consensus on Topical Dutasteride in 2024?

in Finasteride/Dutasteride 146 upvotes 6 months ago

The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

community Been on homemade topical finasteride ( 0,025% ) for well over 2 years, and I just feel I maintain. Prior to that I have been using Rogaine ( Minoxidil foam 5% ) which had thickened the strands of hairs I already had. What changes could I made on my stack to see any further improvement?

in Progress Pictures 3 upvotes 7 months ago

The user has been using homemade topical finasteride for over 2 years with no side effects and Rogaine foam, considering a hair transplant in a year. They are contemplating whether to continue the current treatment, switch to oral finasteride with or without RU58841, and are unsure about potential side effects of oral medication.

community Combining all your topicals into one

in Treatment 3 upvotes 8 months ago

The user is using a hair loss treatment regimen that includes applying various topical solutions and taking oral medication. They are mixing their topical treatments to save time but are concerned about the effectiveness of the treatments when combined and stored.

community Topical Saw Palmetto: An Alternative to Microdosing Topical Finasteride?

in Product 16 upvotes 1 year ago

The user is exploring topical Saw Palmetto as a milder alternative to microdosing topical Finasteride for hair loss, aiming to minimize systemic DHT impact. They plan to experiment with this herbal remedy for a year to assess its effectiveness on their mild androgenetic alopecia without significant side effects.

community PCOS female who posted before; saw Endo today. prescribed spironolactone and minox 5%

in Update 1 upvotes 1 year ago

PCOS female visited doctor for hair loss concerns, prescribed spironolactone and minox 5%. Doctor advised against finasteride or dutasteride, user considering self-medication with dutasteride.

community Topical Dutasteride & Microneedling Works

in Finasteride/Dutasteride 5 upvotes 2 months ago

Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

community finasteride progress… feels like I’m losing ground

in Is this regrowth? 10 upvotes 2 months ago

The user is using finasteride and minoxidil for hair loss but feels progress is slow and is considering switching to dutasteride after 12 months. They notice minor shedding but are unsure if the medication is stabilizing their hair loss.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 127 upvotes 4 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Clascoterone study going on right now

in Research/Science 351 upvotes 6 months ago

A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

community Is it uncommon to not test for testosterone levels before taking fin?

in Finasteride/Dutasteride 13 upvotes 7 months ago

Doctors often prescribe finasteride for hair loss without testing testosterone levels. There is no need for such tests before starting the medication.

community A Nuanced Look at Microdosing Topical Finasteride

in Finasteride/Dutasteride 85 upvotes 11 months ago

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

community 8 months - 0.5mg dut, 80mg Ru58841, 5mg oral min, topical min at night, microneedle 1.5mm every other week

in Progress Pictures 402 upvotes 1 year ago

The conclusion of the conversation is that the user has experienced significant hair regrowth using a combination of medications, including dutasteride, RU58841, and minoxidil. They have not experienced any noticeable side effects and are considering a hair transplant in the future.