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Glossary Systemic Antibiotics

medications that treat bacterial infections throughout the entire body

Systemic antibiotics are medications designed to combat bacterial infections throughout the entire body, rather than targeting a specific area. They are typically administered orally or intravenously, allowing the active ingredients to circulate through the bloodstream and reach various tissues and organs. This makes them effective for treating widespread or severe infections that cannot be managed with topical treatments alone.

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community Male Pattern Baldness is actually cured

2 years ago

Finasteride and dutasteride are considered the best treatments for male pattern baldness, but they are not cures as they only slow hair loss. Other potential treatments like topical melatonin and natural DHT blockers are discussed, but aging and other factors like inflammation also play roles in hair loss.

community KX-826: My initial thoughts and observations on pyrilutamide...

1 upvotes 1 year ago

The user tried pyrilutamide for hair loss and noticed reduced scalp itch and improved skin but stopped due to mild heart sensations. They plan to update after consistent use, noting improved sleep when applied at night.

community minoxidil alone vs microneedling alone

in Research/Science 29 upvotes 1 year ago

Microneedling alone can stimulate hair growth and enhance the effectiveness of minoxidil. Combining microneedling with minoxidil is more effective than using minoxidil alone.

community Possible regrowth after 4 years of hair loss (with family history of baldness) — could lifestyle changes reactivate follicles?

3 upvotes 4 months ago

The user noticed hair regrowth after 4 years of hair loss, coinciding with lifestyle improvements like quitting smoking, exercising, and a better diet. They are curious if dormant follicles can recover under improved conditions.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Gut microbiome imbalances linked to scalp inflammation and hair follicle impact

in Technology 243 upvotes 4 months ago

Gut microbiome imbalances can cause scalp inflammation and affect hair follicles, potentially leading to hair loss. Treatments include finasteride, peptides like BPC-157, TB-500, KPV, and lifestyle changes such as diet and exercise.

community Amplifica Sees Positive Results for Hair Loss Treatment - Results Show 15% increase in 60 days!

103 upvotes 1 year ago

Amplifica's new injectable treatment for androgenetic alopecia shows a 15% increase in hair thickness and coarseness in 60 days. The treatment is in early human trials and offers a promising alternative to hormone-related hair loss treatments.

community All my gains from minoxidil fell out years later

in Finasteride/Dutasteride 48 upvotes 1 year ago

The user experienced hair loss after initially gaining hair with minoxidil and is now using dutasteride and oral minoxidil alongside topical minoxidil, hoping to regain lost hair. There is uncertainty about the effectiveness of these treatments, with some users suggesting that blocking DHT might help, while others express skepticism about regrowth.

community What if DHT is not the vilan.

13 upvotes 5 years ago

Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

community What I would tell my younger self when I started losing hair

in Chat 197 upvotes 1 year ago

Hair loss is emotionally challenging, but acceptance and focusing on other life aspects are important. Treatments like finasteride, minoxidil, and RU58841 are discussed, with emphasis on the emotional impact over physical changes.

community I am putting my hair loss treatment on hold until my mental health is better.

in Update 21 upvotes 2 years ago

OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.

community CAUTION: My Experience with RU58841

13 upvotes 2 years ago

The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

community The hardest hair protocol ever!

9 upvotes 4 years ago

The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Ru58841 ruined my life. Here’s why.

132 upvotes 4 years ago

User experienced shortness of breath, high blood pressure, red eyes, and eye floaters after using RU58841 for hair loss. They warn others to avoid RU58841 and stick to finasteride, minoxidil, and dutasteride.

community Is it me or are people losing their hair very young now?

in Finasteride/Dutasteride 143 upvotes 6 years ago

People notice more young individuals experiencing hair loss and discuss possible reasons, such as diet, hormones, and stress. Some treatments mentioned include finasteride, dutasteride, and minoxidil.

community With studies showing that 0.2mg Finasteride is almost as effective as 5mg at reducing DHT, why is every doctor prescribing 1mg?

252 upvotes 9 months ago

Finasteride is prescribed at 1mg because it is FDA-approved and proven effective, despite evidence that 0.2mg may similarly reduce DHT. The 1mg dose is more effective for hair growth, and lower doses are less available.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community I just made 60x of 5mg minoxidil sugar cubes

1339 upvotes 1 year ago

A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

community Why is everyone not directly advised Dutasteride?

in Finasteride/Dutasteride 169 upvotes 1 year ago

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 2 years ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 2 years ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

37 upvotes 7 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

community Non-systemic hair loss stack, is there any hope?

6 upvotes 2 weeks ago

A 19-year-old is experiencing hair thinning and has tried various doses of oral and topical finasteride but faced psychological and sexual side effects. They are considering topical anti-androgens like KX826, ketoconazole cream, and RU58841 as alternatives, while others suggest clascoterone and topical dutasteride.

community Minimizing systemic DHT reduction with topicals

5 upvotes 3 weeks ago

The conversation discusses minimizing systemic DHT reduction using topical treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and a proprietary carrier for DUT by XYON Health. The focus is on finding effective DHT blockers with minimal systemic absorption.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Any treatment not nuking systemic DHT levels?

16 upvotes 6 months ago

Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

5 upvotes 7 months ago

Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

community Does pyrilutamide degrade to an inactive form if it goes systemic like fluridil

1 upvotes 9 months ago

Pyrilutamide's systemic degradation is unclear, unlike fluridil, which becomes inactive in the body. The discussion focuses on whether pyrilutamide shares this property.

community Have you noticed systemic absorption of RU58841?

in Treatment 1 upvotes 10 months ago

The conversation discusses using RU58841 as a topical treatment for hair loss, with some users reporting no systemic issues. The original poster is considering RU58841 due to limited progress with dutasteride and oral minoxidil.