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GlossarySteroid Sulfatase Inhibitors

block enzyme activity to reduce active steroid levels

Steroid Sulfatase Inhibitors (STS inhibitors) are compounds that block the activity of the enzyme steroid sulfatase, which is involved in the conversion of sulfated steroid precursors into active steroids like estrogen. By inhibiting this enzyme, STS inhibitors can reduce the levels of active steroids, potentially offering therapeutic benefits in conditions like hormone-sensitive cancers and certain skin disorders.

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community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 1 year ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community Progress o regress? 2 Years only dermaroller (and RU for only 2 month)

in Is this regrowth? 70 upvotes 1 year ago

The conversation discusses hair loss and treatments, with users suggesting the original poster's hair has receded despite using a dermaroller and RU58841 for two months. Many recommend starting finasteride and minoxidil for better results.

community Not sure what else to do, can’t use anti-androgens (Baseline Hormonal Bloodwork included) need advice badly

in Update 6 upvotes 3 years ago

User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

in Finasteride/Dutasteride 37 upvotes 1 year ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

in Research/Science 74 upvotes 2 years ago

Hair loss and scalp issues, with people discussing possible treatments such as Nizoral shampoo, Minoxidil, neem oil, and finasteride.

community Minoxidil seems to not work anymore this sucks

in Progress Pictures 32 upvotes 1 year ago

A user reported that Minoxidil, a hair growth treatment, stopped working for them despite initial success. Other users suggested not taking breaks from the treatment, checking for fake products, trying microneedling, using oral Minoxidil, combining Minoxidil with tretinoin, and using finasteride.

community How I paused my hair loss by curing seborrheic dermatitis

in Treatment 107 upvotes 1 year ago

User Wonderful_Tonight910 suffered from hair loss and seborrheic dermatitis for years. After using irritant-free shampoo, their scalp improved, hair loss stopped, and new hair growth appeared.

community What’s the most effective way to beat Serb Derm?

in Treatment 7 upvotes 2 months ago

OP struggles with scalp flakes causing hair loss and has tried Selsun Blue, Ketoconazole, and ZPT Shampoo without success. Suggestions include using salicylic acid shampoo, shaving the head, using Nizoral, and combining treatments like Minoxidil and finasteride.

community Have been on treatment for close to two years, need to know if I should continue or take dut

in Progress Pictures 52 upvotes 2 months ago

A 22-year-old male has been using finasteride, topical minoxidil, and oral minoxidil for hair loss but sees minimal improvement and is considering adding dutasteride. Users suggest additional treatments like dermarolling, PRP, and consulting a dermatologist, or considering a hair transplant.

community Why the fu*k do people behave like this?

in Chat 385 upvotes 1 year ago

People making comments on others' hair loss, and the different strategies used to deal with it. Treatments mentioned include finasteride and minoxidil.

community Surprise! Hair loss at 25

6 upvotes 8 years ago

A user noticed worsening hair loss and is considering treatments. They plan to use finasteride, Rogaine, and a ketoconazole shampoo, and seek advice on their effectiveness and usage.

community Steroid injections helped my hair loss but I have AGA?

in Female 1 upvotes 7 months ago

A woman with AGA and CTE has been taking multiple hair loss treatments including spironolactone, dutasteride, finasteride, bicalutamide, birth control, and minoxidil without success. Steroid injections, however, dramatically and immediately stopped her hair loss, though the effect lasts less than a month.

community My hair after 3 steroid cycles

in Progress Pictures 25 upvotes 4 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 6 months ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Can I use topical steroid along finasteride to reduce scalp inflammation and hairloss?

in Finasteride 6 upvotes 5 years ago

The user asks if finasteride can be used with the topical steroid betamethasone dipropionate to reduce hair loss and scalp inflammation. The discussion revolves around combining these treatments for better results.

community Ru-58841 vs KX-826/pyrilutamide while on steroids

in Finasteride/Dutasteride 3 upvotes 3 weeks ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

community This and ketoconazole 2% life changing

in Ketoconazole 69 upvotes 1 year ago

The post discusses the user's experience with hair loss treatment using finasteride, clobetasol propionate, and ketoconazole shampoo. The conversation warns about the potential side effects of clobetasol, a powerful topical steroid, and emphasizes its short-term usage.

community 21 Y.O, lost a lot of hair. Made an elaborate plan to get it back, this is the beginning of my log

8 upvotes 7 years ago

A 21-year-old experienced significant hair loss after steroid use and stopping minoxidil. He plans to regrow his hair using a regimen of dermarolling, Lipogaine, finasteride, and vitamins.

community Is hydrocortisone that bad for your scalp?

in Minoxidil 1 upvotes 1 month ago

Hydrocortisone is not recommended for long-term use on the scalp due to potential side effects like thinning and steroid-related issues. Alternatives like foam minoxidil or oral minoxidil are suggested, though foam may be less effective.

community As in this research, i have seen many who advise a regular use of VitaminD, even if you are not deficient. Once i had read in tressless that mpb and Vitamin D might have a correlation. So could it be an a benefit to add this to your ongoing treatment plan?

in Research/Science 83 upvotes 4 years ago

People discussed using vitamin D supplements for hair loss, with some also using steroid injections, pumpkin seed oil, saw palmetto, and zinc. Despite supplementation, one user noted no improvement in hair condition, but acknowledged the general health benefits of addressing vitamin D deficiency.

community formula 82D for diffuse androgenic alopecia (DUPA)

in Is this regrowth? 14 upvotes 1 week ago

The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

community Tristan Tate stopped using fin i guess???

in Satire 468 upvotes 2 months ago

Tristan Tate's hair loss is discussed, with mentions of finasteride, minoxidil, and dutasteride as treatments. Users speculate on his hair styling, steroid use, and legal troubles.

community Starting Treatment for CCCA (scarring alopecia)

in Treatment 6 upvotes 1 year ago

A male in his early 20s with CCCA (scarring alopecia) started treatment with Finasteride, Fluocinolone, and Doxycycline. Steroid injections were suggested but not yet done.

community Covid (likely) induced alopecia areata - now 2nd round of Covid, what can I expect?

in Treatment 1 upvotes 1 year ago

After experiencing hair loss due to alopecia areata following COVID-19 vaccination and infection, the individual saw improvement with steroid treatments and Olumiant. They paused Olumiant during a second COVID-19 infection and expressed concern about potential hair loss flare-ups.

community No Luck Getting Rid Of The Itchy Scalp. What Now?

in Chat 10 upvotes 2 years ago

A user experienced a burning, itchy scalp and hair thinning despite trying finasteride, steroid cream, antihistamines, various shampoos, and supplements. They seek advice on relieving the itch, hoping it will improve hair health.

community Chris Bumstead Hair Tansplant at Now Hair Time

in Transplants 476 upvotes 11 months ago

Chris Bumstead got a hair transplant at Now Hair Time, and the discussion focuses on why he chose a less reputable clinic despite having the means for a better one, with some suggesting it was for financial gain. The conversation also touches on concerns about the naturalness of the hairline and the potential impact of his steroid use on the transplant's success.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community New approach: oral and topical min

in Progress Pictures 6 months ago

The user is trying a new hair loss treatment combining 1.25 mg oral minoxidil with a daily topical solution containing hydrocortisone, tretinoin, 8% minoxidil, and 0.025% finasteride. They aim to maintain their current hair before considering a hair transplant in Istanbul.

community CASSIOPEA ANNOUNCES VERY POSITIVE PHASE II TWELVE MONTHS RESULTS FOR BREEZULA® (CLASCOTERONE) IN TREATING ANDROGENETIC ALOPECIA

in Update 162 upvotes 5 years ago

Clascoterone (Breezula) showed positive results for treating hair loss without affecting cortisol levels. Opinions vary, with some users optimistic about its potential and others critical of its effectiveness compared to existing treatments like finasteride.

community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

in Transgender 611 upvotes 1 week ago

The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.