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GlossarySteroid Hormones

regulate various body functions by interacting with cell receptors

Steroid hormones are a class of hormones that are derived from cholesterol and include substances like cortisol, estrogen, and testosterone. They play crucial roles in regulating a variety of physiological processes, such as metabolism, immune response, and reproductive functions. These hormones can pass through cell membranes and bind to specific receptors inside cells, influencing gene expression and cellular activity.

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community Ketoconazole mesotherapy plausible?

in Ketoconazole 9 upvotes 6 months ago

The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.

community How uninformed the general public is about hair loss

in Chat 315 upvotes 9 months ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 1 year ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community For Once and For All: Is It the DHT in the Scalp That Matters, Not the DHT in Your Bloodstream?

in Treatment 82 upvotes 1 month ago

DHT in the scalp, not the bloodstream, is crucial for hair loss. Treatments discussed include finasteride, minoxidil, dutasteride, and microneedling.

community No, Finasteride as a treatment for MPB was not an "accident"

in Research/Science 105 upvotes 3 years ago

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

community What Works to Restore Hairloss for Cis-Males? Not Much

in Treatment 16 upvotes 4 years ago

Hair regrowth treatments for cis-males include Minoxidil, Finasteride, and RU58841. Estrogen and testosterone blockers can help restore hair loss but may not suit everyone.

community What the hell happened in my family genes?

in Chat 116 upvotes 5 months ago

A user is frustrated about early balding despite older male relatives retaining hair into old age. Another user plans to start finasteride soon to address their hair thinning.

community Fluridil downregulates androgen receptor expression?

in Research/Science 1 upvotes 9 months ago

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.

community My hair after 3 steroid cycles

in Progress Pictures 27 upvotes 4 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 5 months ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Topical finasteride has affected my hormones

in Finasteride/Dutasteride 26 upvotes 10 months ago

A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

community 21 Y.O, lost a lot of hair. Made an elaborate plan to get it back, this is the beginning of my log

8 upvotes 7 years ago

A 21-year-old experienced significant hair loss after steroid use and stopping minoxidil. He plans to regrow his hair using a regimen of dermarolling, Lipogaine, finasteride, and vitamins.

community Hair loss treatment rabbit hole [OC]

in Satire 317 upvotes 2 years ago

Hair loss treatments, ranging from topical minoxidil and finasteride to taking hormones such as estradiol or nandrolone, as well as a controversial suggestion of an orchiectomy. A hair system is also mentioned as an alternative solution.

community Help interpreting pre-fin bloodwork

in Finasteride/Dutasteride 13 upvotes 3 years ago

A 20-year-old male is unsure how to interpret his bloodwork results and whether he should take finasteride for hair loss. His bloodwork shows borderline high levels of albumin and testosterone, and high progesterone, but normal levels of other hormones.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community C’est terrible - at my wits end

in Female 442 upvotes 11 months ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Treating my DUPA via controlling inflammation

in Treatment 6 upvotes 9 months ago

The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

community Ru, Stemoxydine or Alfatradiol? What has your experience been with any of these 3?

in Treatment 3 upvotes 1 year ago

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

community I'm regrowing my hair while being on the harshest steroids

10 upvotes 6 years ago

The user is regrowing hair while using steroids by following a regimen that includes Rogaine, RU58841, Dutasteride, Nizoral, PGE2, and occasionally castor oil. Despite using harsh steroids like Tren, Masteron, and Proviron, the user reports successful hair regrowth.

community I’m just Going to let Nature take its Course

in Chat 213 upvotes 1 year ago

The post and conversation are about a 23-year-old deciding to stop using finasteride for hair loss due to potential erectile dysfunction risks, sparking a debate about the benefits and side effects of hair loss treatments.

community My experience with Alfatradiol so far

in Treatment 10 upvotes 1 year ago

User is 16, experiencing hair loss, and using minoxidil and alfatradiol. Shedding decreased, new hairs growing on temples, but unsure if alfatradiol is effective or if future shedding will occur.

community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry

in Transgender 137 upvotes 2 years ago

Hair loss discussion mentions using estrogen mixed with growth stimulants like oral minoxidil for scalp hair growth. Idea proposed for an artificial SARM-estrogen that only affects hair without body side effects.

community New stack I started this year has ruined my hair

in Finasteride/Dutasteride 6 upvotes 6 days ago

Switching from finasteride and topical minoxidil to oral minoxidil and dutasteride worsened hair condition, leading to frustration and heart issues, prompting a return to topical treatments and the addition of tretinoin. Patience and consistency are advised, as these treatments can take years to show results, and abrupt changes may cause shedding.

community How did you get over the fear mongering of Fin/Dut?

in Finasteride/Dutasteride 62 upvotes 2 months ago

The conversation is about overcoming fear of finasteride/dutasteride for hair loss treatment. Users suggest starting with a small supply, noting side effects are rare and reversible, and emphasize personal comfort and confidence.

community What Private blood test should I take?

in Finasteride/Dutasteride 7 upvotes 3 months ago

A user in the UK seeks advice on blood tests before starting Finasteride and Minoxidil for hair loss. Recommended tests include thyroid function, hormone levels, liver and kidney function, and vitamin and mineral levels.

community Gyno & testoterone level

in Finasteride 282 upvotes 4 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

community high estrogen levels after 10month fin

in Finasteride/Dutasteride 9 upvotes 1 year ago

A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 1 year ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community Nandrolone Replacement Therapy

in Treatment 41 upvotes 1 year ago

A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.