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GlossaryStem Cell Secretome

collection of bioactive molecules secreted by stem cells

The stem cell secretome refers to the collection of bioactive molecules, such as proteins, lipids, and nucleic acids, that are secreted by stem cells. These molecules play a crucial role in cell communication, tissue repair, and regeneration by influencing the behavior of surrounding cells. For professionals, understanding the stem cell secretome is essential for developing therapies for conditions like alopecia, where promoting hair follicle regeneration is key.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Calecim (PTT-6) Advanced Hair System with Topical Exosomes and Growth Factors for Hair Growth

in Treatment 3 months ago

Calecim (PTT-6) Advanced Hair System is a 6-week hair restoration product using stem cell-derived ingredients to stimulate hair growth. Users are skeptical, calling it overpriced and ineffective, suggesting alternatives like LLLT devices or PRP treatments.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 7 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community My microneedling journey (no min, fin, etc)

in Microneedling 208 upvotes 2 months ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

community Chris Bumstead Hair Tansplant at Now Hair Time

in Transplants 477 upvotes 1 year ago

Chris Bumstead got a hair transplant at Now Hair Time, and the discussion focuses on why he chose a less reputable clinic despite having the means for a better one, with some suggesting it was for financial gain. The conversation also touches on concerns about the naturalness of the hairline and the potential impact of his steroid use on the transplant's success.

community STEM CELL TREATMENT FOR HAIR LOSS at home

in Treatment 6 upvotes 3 years ago

User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.

community Mesenchymal Stem Cell Therapy (Exosome) Before & After

in Treatment 2 upvotes 8 months ago

A user's father experienced hair regrowth and other health improvements after two IV exosome treatments. The user also had four rounds of exosome therapy, noting significant hair regrowth and relief from headaches, but no change in gray hair.

community Seeking Advice: Stem Cell Therapy vs. PRP for Hair Loss

in Treatment 2 upvotes 7 months ago

The conversation is about someone seeking advice on choosing between stem cell therapy and PRP for treating hair loss, asking for personal results, side effects, overall satisfaction, and recommendations from others.

community PP405 - hair stem cell stimulation

in Research/Science 51 upvotes 9 months ago

PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

community redensyl - follicle stem cell activator any experiences?

in Question 9 upvotes 7 years ago

A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.

community Does PRP, Exosome therapy, peptides, Stem Cell - any of 'em work?

in Research/Science 2 upvotes 1 year ago

The conversation discusses hair loss and queries the effectiveness of treatments like PRP, Exosome therapy, peptides, and Stem Cell therapy. Specific treatments like Minoxidil, finasteride, and RU58841 are also mentioned.

community Stem Cells May Get Rid Of Balding FOREVER!

in Technology 7 upvotes 5 months ago

Stem cell therapy shows promise in treating hair loss by mimicking DHT-resistant cells from the back of the head. Traditional treatments like finasteride are also discussed, but stem cells could potentially offer a more permanent solution.

community This guy claims stem cells fixed his balding

in Is this regrowth? 301 upvotes 1 year ago

A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

community I am not losing my hair (yet) and do not think I will soon, but I am a pre medicine major who has an obsession over stem cells and want to share something with you all. Your future is brighter than you think.

19 upvotes 7 years ago

User hoodoomoovoo discusses their interest in stem cell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.

community 1.5 Year Hair Restoration Journey - Stem Cells, PRP, Minoxidil, Topical Finasteride

in Progress Pictures 27 upvotes 10 months ago

A user shared their 1.5-year hair restoration journey, successfully using mesenchymal stem cell therapy, Platelet Rich Plasma (PRP) injections, and a topical compound of finasteride and minoxidil, avoiding a hair transplant and oral finasteride. They experienced significant hair regrowth, particularly crediting the stem cell therapy for quick initial results.

community If the main mechanism of microneedling is an increase in bloodflow to the scalp, shouldn't we be pursuing other actions which increase bloodflow? Sauna, cold showers, high dosage fish oil, hard cardio, heme-iron(red meats), HAND STANDS, foods high in NO (arugula), ginger, increased water consumption

in Question 17 upvotes 5 years ago

Microneedling stimulates hair growth through stem cell activation during wound healing, not just increased blood flow. Other methods like showers or supplements don't replicate this effect.

community How Does Exosome Therapy Work for Hair Loss?

in Research/Science 5 upvotes 1 year ago

Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

community Any promising new research or techniques for hair loss treatment and hair transplants?

in Research/Science 5 upvotes 5 days ago

The conversation discusses new hair loss treatments like stem cell therapy, exosome treatments, and DHI, with mentions of GT20029, Amp303, and Plated PRP Serum as promising options. It also notes the use of dutasteride, topical finasteride, and minoxidil, but the focus is on non-hormonal innovations.

community Does microneedling regrow hair on dormant bald regions which have been bald for many years?

in Microneedling 6 upvotes 4 years ago

Microneedling may help regrow hair in dormant bald regions by stimulating stem cell transfer. Users discuss its effectiveness and how collagen might aid in the process.

community TGF-Beta. Good or Bad? Help for treatment investment

in Treatment 13 upvotes 2 years ago

TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.

community OMG INTERVIEW W/ DR TSUJI - The GOD of Hair Cloning! MUST WATCH

in Research/Science 21 upvotes 3 years ago

The conversation discusses an interview with Dr. Tsuji about hair follicle stem cell multiplication and the financial challenges of starting human clinical trials. It also mentions the need for funding to secure a patent for a protein that promotes hair growth.

community How to increase graft survivability after HT?

in Transplants 6 upvotes 5 months ago

A user is seeking advice on increasing graft survivability after a hair transplant, mentioning PRP, Mesotherapy, Stem Cell injections, and considering L-Arginine before starting Minoxidil. They are looking for ways to support blood flow before applying Minoxidil.

community 3 month progress NW5 -- lost cause?

in Progress Pictures 22 upvotes 2 years ago

A user is treating their advanced hair loss with a regimen including topical finasteride, minoxidil, hydrocortisone, stem cell serum, peptide serum, multivitamins, he shou wu tea, derma pen, argan oil, and a derma roller. Replies suggest it's too early to judge progress and recommend staying consistent, with one suggesting oral minoxidil as an additional option.

community Anyone Try Microneedling with Exosomes/AAPE?

in Microneedling 2 upvotes 2 years ago

User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

community Is There Any Chance Of Cancer In Follicle Neogenesis through Microneedling?

in Microneedling 15 upvotes 4 years ago

The conversation discusses concerns about the potential risk of cancer from creating new hair follicles through microneedling, due to stem cell division. Specific treatments mentioned include microneedling, caffeine-containing anti-hair loss shampoos, and other unspecified topicals.

community How it looks a shaved head that went through a FUE Hair Transplant after 5-10 years? (Both donor and recipient area)

in Transplants 44 upvotes 5 years ago

Celonius discusses hair loss and plans for a FUE Hair Transplant, but worries about how it will look when shaved in the future. Derhab21 suggests going for the transplant and mentions potential future treatments like Breezula and stem cell injections.

community Injecting stomach fat into the scalp could cure baldness in just six months

in Update 114 upvotes 6 years ago

A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

community Kintor Pharma Announces Completion of First Patient Enrollment in Phase II Clinical Trial of GT20029 for Treatment of Androgenetic Alopecia in China.

in Research/Science 133 upvotes 1 year ago

Kintor Pharma has started a Phase II trial in China for GT20029, a potential new treatment for hair loss. Participants are discussing the significance, potential release dates, and comparing it to other treatments and technologies like stem cell hair transplants and SAMIRNA.