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GlossarySolubility

ability of a substance to dissolve in a solvent

Solubility is the ability of a substance (solute) to dissolve in a solvent, forming a homogeneous mixture at a specified temperature and pressure. For example, sugar has high solubility in water, meaning it can dissolve easily to form a sweet solution. This concept is crucial in fields like pharmacology, where the solubility of a drug affects its absorption and efficacy.

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community Can you dissolve fin pills in stemoxydine ?

in Finasteride/Dutasteride 2 upvotes 2 weeks ago

Mixing finasteride pills with stemoxydine is not recommended due to potential solubility and safety issues. It's advised to consult a healthcare provider for professionally formulated topical finasteride products.

community Making topical finasteride solution

in Finasteride/Dutasteride 1 upvotes 9 months ago

The user has been mixing finasteride with stemoxydine for hair loss and is considering switching to a less expensive product with a different ingredient list. They are questioning if the new product's higher water content compared to alcohol will affect the finasteride's solubility.

community The New, Improved CB-03-01/Setipiprant Group Buy

29 upvotes 8 years ago

The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

community Best vehicle for topical melatonin?

in Treatment 6 upvotes 3 years ago

The conversation is about creating a homemade solution for hair loss treatment, specifically asking for advice on what base to use for topical melatonin. No specific treatments were discussed.

community If you could get for Christmas your own personalised topical anti hair loss serum that has the best the current science can offer, what would it contain and at what concentration?

in Treatment 1 upvotes 4 days ago

A personalized topical anti-hair loss serum could include high-dose setipiprant, high-dose CB 03-01, low-dose finasteride, minoxidil, latanoprost, and tretinoin. These ingredients are suggested for their potential effectiveness in promoting hair growth.

community Can use olive oil instead of PG (propylene glycol) or glycerin in topical finasteride preparation?

in Finasteride/Dutasteride 2 upvotes 4 months ago

A user asked if olive oil can replace propylene glycol or glycerin in topical finasteride preparation. Another user advised against it, suggesting MCT oil instead due to olive oil's potential to worsen dandruff and seborrheic dermatitis.

community Currently crushing 3 (5mg) tablets of fin into my topical min. Anyone do the same? If so how much do you add.

in Treatment 186 upvotes 7 months ago

The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.

community Minoxidil BAILLEUL 5% Men - Systematic Crystallisation In Sprayers and Bottles

in Minoxidil 2 upvotes 10 months ago

The post discusses issues with Minoxidil BAILLEUL 5% Men, specifically sprayer clogging and crystallization in bottles. Recommendations include rinsing the sprayer and soaking the bottle in hot water to dissolve crystals, with calculations suggesting the product remains effective despite these issues.

community This serum outperformed Minoxidil in a recent study. Please debunk

23 upvotes 5 years ago

A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?

in Finasteride/Dutasteride 41 upvotes 2 weeks ago

Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.

community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?

in Finasteride/Dutasteride 22 upvotes 5 months ago

Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.

community Best carrier for pyrilutamide?

in Update 9 upvotes 2 years ago

The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Selling a premixed KY19382 solution

in Research/Science 8 upvotes 3 years ago

The conversation discusses the sale of a premixed KY19382 solution for research purposes, highlighting previous unsuccessful group buys and the formulation process. Prices and purchasing options for KY19382 solutions and powder are provided.

community Why is no one talking about redensyl?

in Question 58 upvotes 4 years ago

Exploring the effectiveness of redensyl, a hair loss treatment, compared to minoxidil and finasteride. People shared experiences using redensyl and products containing it, such as The Ordinary Hair Serum.

community I just made 60x of 5mg minoxidil sugar cubes

in Minoxidil 1323 upvotes 4 weeks ago

A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

community Topical Finasteride strength discussion

in Research/Science 65 upvotes 10 months ago

The conversation discusses the effectiveness of different concentrations and dosages of topical finasteride on scalp and serum DHT levels, comparing it to oral finasteride and noting the side effects seem to be fewer at lower dosages. Participants shared experiences and referenced a chart indicating similar scalp DHT reduction with 0.025% topical finasteride as with 1mg oral finasteride, but with fewer side effects.

community Does melatonin dissolve in isopropyl alcohol

in Technology 7 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Creating Your Own Topicals: A Guide

in Research/Science 71 upvotes 1 year ago

Creating a carrier solution for topical hair loss treatments using ethanol, propylene glycol or glycerin, and instructions on creating topical finasteride. Different recipes are provided with varying ratios of alcohol to humectant.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 441 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Thinking about my making own CB-03-01 (Breezula). Thoughts?

in Treatment 7 upvotes 4 years ago

The user experienced side effects with both oral and topical finasteride and is considering making their own hair loss treatment using CB-03-01 (Breezula) mixed with minoxidil due to fewer reported side effects. They plan to use a lower concentration than what was used in trials.

community Would Fluridil and Alfatradiol work effectively in conjunction with each other?

in Treatment 10 upvotes 4 years ago

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

community Any young women losing hair that have tried microneedling and oils?

in Microneedling 32 upvotes 4 years ago

A 25-year-old woman is experiencing hair loss and has started microneedling with a 0.5mm roller, applying a mix of essential oils overnight. She questions whether to switch to a 1.5mm roller and the best order for her routine, while a reply suggests using Minoxidil for better results.

community First bottle of Morr-F arrived. Wish me luck, and an introduction.

11 upvotes 5 years ago

A user discusses their experience with hair loss and treatments, including minoxidil, micro needling, rosemary oil, dietary supplements, and topical finasteride (Morr-F). They emphasize the impact of lifestyle on hair health and express hope for improvement with the new treatment.

community HUGE: Pyrilutamide seems to be stable for at least 3 weeks into KB solution. So, that means stable with water content and not degradation according to Anageninc! They will keep testing the stability further. Check the video! Many thanks to the guy AlphaMode.

in Update 68 upvotes 1 year ago

The potential stability of pyrilutamide in a mixture with water, and how it could be used in combination with Minoxidil and Finasteride to treat hair loss.