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GlossarySkin Microenvironment

complex and dynamic environment within the skin influencing health

The skin microenvironment refers to the complex and dynamic environment within the skin, including various cell types, extracellular matrix components, and signaling molecules. It plays a crucial role in maintaining skin health, influencing processes like wound healing, immune responses, and hair growth. Understanding the skin microenvironment is essential for developing treatments for conditions like alopecia and other skin disorders.

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community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 3 weeks ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 121 upvotes 5 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 5 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community Why I really believe the tension theory is the cause of MPB

in Research/Science 70 upvotes 3 years ago

The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.

community Skin, Hair, and Nails by Pharmekal withdrawn from the market

in Product 1 upvotes 1 year ago

Skin, Hair, and Nails by Pharmekal was withdrawn from the market. Users discuss alternative supplements and treatments like Minoxidil, finasteride, and RU58841.

community My skin is always dry and flakes like chalk (25)

in Transgender 6 upvotes 6 months ago

The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

community Personal Anecdote: Be careful with oral min, it can have a bad impact on your skin

in Minoxidil 4 upvotes 9 months ago

Oral minoxidil can cause skin issues like redness and bumps. The user saw no hair improvement with oral minoxidil but noticed increased facial hair.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 62 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Anybody else notice improved skin/collagen on Dutasteride

in Finasteride/Dutasteride 6 upvotes 1 year ago

User switched from finasteride to combination dutasteride and finasteride for hair density improvement. They noticed less hair shedding and more youthful skin, with a reply suggesting less DHT could increase elastin in skin.

community Oral minoxidil can causes age skin?

in Minoxidil 8 upvotes 2 years ago

Oral minoxidil may cause skin aging, such as dark circles. To counteract aging, use tretinoin at night and broad-spectrum sunscreen during the day.

community Minoxidil and skin aging worry – which prevention methods (platelet rich plasma, microneedlig, mesotherapy, stem cells, co2, ultherapy, …)

in Chat 4 upvotes 2 years ago

User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.

community Topical application of Apple Skin 15% Procyanidin B2 extract makes hair noticeably thicker

in Treatment 7 upvotes 2 years ago

Hair loss discussion includes homemade 15% Procyanidin B2 apple skin extract as alternative to Minoxidil. User reports thicker hair, but no new growth yet.

community Can Minoxidil be Aging My Skin?

in Minoxidil 6 upvotes 2 years ago

Minoxidil may cause skin aging effects like wrinkles and dark circles, but evidence is mixed. Alternatives like dermarolling and retinol are suggested.

community Collagen/Vitamins/Supplements and skin-care routine while on Minoxidil?

in Minoxidil 29 upvotes 4 years ago

Minoxidil users discuss skin-care routines to counteract side effects like dark circles and dull skin. Recommendations include vitamin C, potassium, collagen, retinol, nizoral shampoo, and emu oil.

community Tretinoin can enhance the skin permeability of Minoxidil approximately 3-fold at 0.05%[24] and itself has some hair regrowth properties.

7 upvotes 9 years ago

The conversation discusses enhancing Minoxidil absorption for hair loss treatment using Tretinoin and MSM (Methylsulfonylmethane). The user is seeking sources for Tretinoin and mentions MSM's potential to improve the absorption of topical agents.

community So does oral minoxidil age your skin or not

in Minoxidil 41 upvotes 7 months ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Start taking care of your skin and hair loss TODAY! I was telling myself I didn’t care, but I think the difference in my facial expression says it all. Take action asap before more permanent damage is done. I hope I can inspire some of you, because it’s so worth it. Not for others, for yourself! <3

in Progress Pictures 583 upvotes 2 years ago

User shared progress in treating hair loss and improving skin, using treatments like finasteride, minoxidil, RU58841, tretinoin, microneedling, and skin care regimen. Others commented on the impressive results and asked about costs and side effects.

community For those of you who are getting facial skin side effects (aging, dark circles) from minoxidil, try this, it helped me.

in Minoxidil 11 upvotes 3 years ago

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

community What's the consensus about Minoxidil and skin aging/effects?

in Minoxidil 8 upvotes 4 years ago

The conversation discusses concerns that Minoxidil may cause skin aging, like collagen depletion and puffier faces. Some users suggest that a good skincare routine or collagen supplements might prevent these effects.

community Low-dose oral minoxidil and skin aging

in Minoxidil 7 upvotes 5 years ago

The conversation discusses the use of low-dose oral minoxidil for hair loss and its potential effects on skin aging. Users shared experiences, with some noting side effects like puffy eyelids and dark circles, but no conclusive evidence of significant collagen depletion or increased wrinkles.

community I asked my dermatologist about minoxidil's skin aging side effects

in Minoxidil 30 upvotes 5 years ago

A dermatologist stated that minoxidil does not cause skin aging, despite online claims. A study found no significant impact of minoxidil on collagen content or skin aging.

community Min users : Who can name a specific product that offset the development of Min-related lines and wrinkles in your skin ? There are lots of vague 'try Retinol-A' or 'Zinc' or this or that, but has anyone actually gone and got some shit and had it halt wrinkling ?

in Question 6 upvotes 7 years ago

The conversation discusses treatments to counteract skin wrinkles caused by Minoxidil use. Suggestions include Retinol-A and Zinc, but users seek specific products that have effectively halted wrinkling.

community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.

in Chat 12 upvotes 8 months ago

The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.

community Tip for anyone who is worried about minoxidil messing up their skin

in Minoxidil 39 upvotes 3 years ago

Use retin-a cream and maintain a good skincare routine to counteract skin issues caused by topical minoxidil. Taking sublingual minoxidil can also be beneficial.

community The science on Minoxidil and its effect on collagen production / skin aging?

in Minoxidil 7 upvotes 4 years ago

User is concerned about starting minoxidil due to potential effects on collagen production and skin aging. They have been using finasteride for almost 2 months.

community Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid????

1 upvotes 6 years ago

The post discusses using a topical tincture containing zinc, azelaic acid, and other ingredients to inhibit 5 alpha-reductase activity for treating hair loss. The user plans to try this natural alternative before using finasteride or RU58841.

community Tretinoin to Counter-Act Minoxidil Related Facial Aging? And other skin care to counteract

in Minoxidil 4 upvotes 5 months ago

The user discusses using Minoxidil and Finasteride for hair loss and plans to counteract potential facial aging from Minoxidil with tretinoin, a jade roller, dandelion root extract, and careful water and sodium intake. They also consider switching to topical Minoxidil and using supplements to enhance treatment response.

community It is said that minoxidil decreases collagen production. Any anecdotes here that have quit minoxidil and got better skin as a result?

in Minoxidil 9 upvotes 1 year ago

Minoxidil is discussed for its potential to decrease collagen production, with users sharing experiences about skin improvement after stopping its use. Some mention using it on their face for beard growth.

community allergen of the year award list(2000-2023).most allergens are in every day shampoos and skin care.

in Research/Science 4 upvotes 1 year ago

The post discusses allergens in everyday shampoos and skincare products, listing yearly allergens from 2000 to 2023. It suggests that these chemicals might contribute to acne and hair loss.

community Big Fin and Big Minox When They Hear Verteporfin Might Replace Messing With Hormones Blood Pressure and Skin

in Satire 41 upvotes 2 years ago

Hair loss treatments, such as minoxidil and finasteride, being replaced by verteporfin, with humorous responses.