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GlossaryEpithelial Stem Cells

cells that regenerate and repair skin and hair follicles

Epithelial Stem Cells are a type of stem cell found in the epithelial tissues, which line the surfaces and cavities of organs and structures throughout the body, including the skin and hair follicles. These cells have the unique ability to self-renew and differentiate into various specialized cell types, playing a crucial role in tissue repair, regeneration, and maintaining the integrity of the epithelial layers.

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community Microneedling and aloe vera to recruit stem cells.

capilluscare in Chat 11 upvotes 1 year ago

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 823 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community This is the best time in human history to be fighting hair loss

ToughEast838 in Treatment 194 upvotes 2 years ago

This conversation discusses the advancements in treatments for hair loss, including finasteride, dutasteride, minoxidil and new promising treatments such as pyrilutamide and verteporfin. Other treatments discussed were taking minoxidil orally, tretinoin to turn non-responders into responders and microneedling to further boost growth.

community UPDATE: The theory that explains everything. Please help me make this big!

joaopassos4444 in Research/Science 448 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community TWIST-1 and the cure: Is it really that easy?

ProposalInside7538 in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community HairClone developing cell replacement treatments for Hair Loss

HairClone 6 upvotes 6 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community Is it possible for androgenic alopecia to begin at early adolescent years?

Uncle__Sheogorath in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community SAFFLOWER OIL good alternative for Minoxidil?

Kaiox9000 in Treatment 1 upvotes 5 years ago

Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

andreas_jacob in Finasteride/Dutasteride 37 upvotes 1 year ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

community Unofficial Dermapen/Roller Guide

X211499Reddit in Treatment 251 upvotes 6 years ago

Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

community Dr Huberman - Cafeine when rubbed on the scalp can be as effective at times as minoxidil because it triggers 1GF-1

eddsters in Update 268 upvotes 1 year ago

Whether topical caffeine can be as effective for hair growth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.

community Long term finasteride users; Did you notice any improvement after 2 years?

SimmaG98 in Finasteride/Dutasteride 14 upvotes 1 year ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

DSBarreto in Research/Science 479 upvotes 6 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

MENSCRIPT in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Sandalore: a scientific homemade approch

gioolio 20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community Why a lot of people seems to hate on topical fin even though it suppresses more scalp dht?

Slow_Pay6229 in Chat 20 upvotes 4 months ago

Topical finasteride may reduce more scalp DHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.

community Metal particles abraded from dermapen (or dermaroller) needles. Is it possible?

Vincent-B in Microneedling 1 upvotes 4 years ago

Concerns about metal particles from dermapen or dermaroller needles potentially entering the skin and lymph nodes, similar to tattoo needles. Discussion includes the possibility of using Minoxidil, finasteride, and RU58841 for hair loss treatment.

community I really wish I started Propecia sooner

Vast_Jaguar_7210 in Finasteride/Dutasteride 2 years ago

A 27-year-old man's experience with taking Finasteride to treat hair loss and the positive side effects he has experienced, such as improved skin. The user also shared their journey of how they were scared away from taking Finasteride due to fear of possible side effects before eventually deciding to take it.

community Serum DHT levels variation on dutasteride

ggyymm96 in Treatment 1 year ago

Serum DHT levels and their variations when using dutasteride for hair loss treatment.

community VERDICT: Do I need microneedling if I run oral minoxidil?

ImportantBlood4641 in Microneedling 30 upvotes 1 year ago

This conversation discusses the effectiveness of microneedling for hair loss, particularly when used in combination with oral minoxidil and finasteride. It is suggested that microneedling alone can be more effective than topical minoxidil alone, but it won't have a synergistic effect with oral finasteride. Advice was also given regarding researching treatments further before taking action.

community Is topical Minoxidil not meant for frontal baldness?

prf_q in Minoxidil 93 upvotes 2 years ago

The effectiveness of topical Minoxidil for frontal baldness and the differences between brands. Suggestions are made to use Finasteride and RU58841 in combination with Minoxidil to help treat hair loss.

community Anyone else have sneezing reflex when starting microneedle?

definitivelynottake2 in Microneedling 55 upvotes 8 months ago

Microneedling can cause a sneezing reflex due to tingling in the nose. Users report this reaction, especially in the temple region.

community I want to know more about hair growth and vitamin D

know_your_nong in Chat 10 upvotes 1 year ago

People discussed vitamin D deficiency and its link to hair loss. One user added cod liver oil to their regimen to boost vitamin D.

community Received a hair transplant today at 22 years old

beaterlife in Transplants 108 upvotes 5 years ago

A 22-year-old's experience with receiving a hair transplant and the use of Minoxidil, finasteride, RU58841, Lidocaine shots, and platelet injections to treat hair loss.

community Finasteride won’t make all your problems go away

idhke in Finasteride/Dutasteride 323 upvotes 1 year ago

A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

community 3 months of only minox + dermarolling, really happy with the results so far

thenewrichardpryor in Progress Pictures 698 upvotes 3 years ago

User experienced hair regrowth with minoxidil and dermarolling for 3 months. Routine includes applying 1ml minoxidil nightly and dermarolling with 0.5mm needles twice a week.

community How to BECOME a RESPONDER to Fin/Dut if you are not responding

DuckSeasonCamelSeasn in Finasteride/Dutasteride 306 upvotes 1 year ago

The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.

community About 1 year of progress: Fin / Min / Microneedle / Nizoral

BigBashMan in Progress Pictures 158 upvotes 1 year ago

The user "BigBashMan" shared their progress pictures of hair regrowth after using a regimen of finasteride, minoxidil, microneedling, and Nizoral shampoo for about a year. They are happy with the results and attribute the microneedling as a potential factor for regrowth. Another user commented that they may see complete scalp coverage in another year.

community Microneedling technique clarification

ThatIsFarEnough in Microneedling 16 upvotes 7 months ago

The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.