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GlossaryPotassium Channels

specialized proteins that regulate potassium ion flow in cells

Potassium channels are specialized proteins found in the cell membrane that allow potassium ions (K+) to pass in and out of the cell. They play a crucial role in maintaining the cell's electrical balance and are essential for various physiological processes, including nerve signal transmission, muscle contraction, and heart function. These channels are highly selective, ensuring that only potassium ions can pass through, which helps regulate the cell's internal environment.

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community Please explain this Minoxidil phenomena

in Minoxidil 60 upvotes 1 year ago

The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

community dunno if it's growing anything but it's making my scalp red

in Technology 182 upvotes 1 year ago

Hair loss and potential treatments, primarily focusing on Finasteride and Minoxidil. Other solutions discussed include PRP, dermarolling, LLP, and scalp tension relief.

community Long term minoxidil as a permanent solution

in Minoxidil 27 upvotes 3 years ago

A user is considering using minoxidil for hair loss and asks for advice on application and long-term effectiveness. Responses suggest minoxidil can be effective but may lose efficiency over time, and combining it with other treatments like finasteride might be more beneficial.

community Solving Hair Loss with Research at MIT

in Research/Science 592 upvotes 1 month ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community For all those worried about a minoxidil break

in Minoxidil 342 upvotes 3 months ago

Stopping minoxidil can lead to significant hair loss, but resuming it along with finasteride can help regain lost hair over time. Consistency is key for maintaining hair health and regrowth.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 444 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 736 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community (comment) providing facts on people talking nonsense about minoxidil and BP-medicaton in general

in Research/Science 17 upvotes 11 months ago

Minoxidil is used for hair loss and sometimes for high blood pressure, but it's outdated for the latter. For high blood pressure, it's combined with a beta blocker and diuretic to manage side effects.

community MY Hair Loss Treatment Summary

in Treatment 8 upvotes 5 months ago

The conversation is about various hair loss treatments, including finasteride, minoxidil, RU58841, and natural supplements like saw palmetto and pumpkin seed oil. It also covers methods to improve blood circulation, nourish hair follicles, and address underlying health issues like vitamin D deficiency and high cortisol levels.

community Does drinking coffee offset the effects of Minoxidil?

in Minoxidil 16 upvotes 7 months ago

The conversation discusses whether drinking coffee affects the hair growth benefits of Minoxidil, with one user mentioning that Minoxidil's vasodilation is stronger than caffeine's vasoconstriction, and another sharing personal experience of better hair growth after quitting caffeine while on Minoxidil.

community 18M 10 months on anti-androgens and oral min

in Progress Pictures 50 upvotes 1 year ago

An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.

community Two months Fin / oral Min, age 48; same lighting, same haircut

in Progress Pictures 466 upvotes 1 year ago

The user "NotYourMothersDildo" shared their progress pictures after using finasteride and oral minoxidil for 60 days. They noticed significant improvements in hair thickness, texture, and growth, including their mustache and beard.

community My experience and hair transformation journey

in Update 68 upvotes 1 year ago

The user improved their hair density and reduced scalp visibility by using 1% ketoconazole shampoo, 1mg finasteride, and 5% minoxidil, which increased their confidence. Replies discuss the effects of these treatments, with one clarifying that minoxidil does not affect hormones but finasteride does.

community Clearing the air on how non-surgical treatments really work

17 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

community 1ish year on fin and no improvement

in Is this regrowth? 86 upvotes 1 month ago

The user has been using finasteride for over a year without improvement and recently started oral minoxidil. Suggestions include trying dutasteride and continuing minoxidil for potential regrowth.

community KX-826: Long-Term Safety Results are out!

in Research/Science 155 upvotes 1 month ago

KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 113 upvotes 1 year ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

in Research/Science 41 upvotes 4 months ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Does Nuking Scalp DHT Theoretically Make Minoxidil Gains Permanent?

in Minoxidil 36 upvotes 1 week ago

Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.

community how it feels to talk to tiktok kids about hairloss that isn’t shitty rosemary oil bloodflow and microneedling

in Satire 988 upvotes 1 month ago

Minoxidil and finasteride are effective for hair loss, especially when used together. Microneedling may enhance minoxidil's effects, but its standalone effectiveness is uncertain.

community Does it look like improvement? 3 months on oral Minoxidil

in Is this regrowth? 800 upvotes 4 months ago

A user shared their 3-month experience with oral Minoxidil and nearly a year on finasteride, asking if a hair transplant might still be needed. Responses varied from congratulatory remarks on visible improvement to advice on sticking with treatments despite initial shedding.

community hairline resurrection — 2 months before/after [5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, weekly 0.5mm dermarolling]

in Progress Pictures 483 upvotes 1 year ago

This conversation was about a user named Substantial_Pen_1099 who has been using an regimen of 5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, and weekly 0.5mm dermarolling for hair loss treatment over the course of 3 months. Others in the conversation expressed disbelief at their progress, to which Substantial_Pen_1099 provided video proof as evidence.

community Could low blood flow to the head cause an increased rate of thinning?

in Chat 27 upvotes 3 years ago

The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hair loss.

community Dont fucking wait to start finasteride!

in Chat 372 upvotes 3 years ago

User baldwarrior85 regrets not starting finasteride earlier to prevent hair loss. Others share their experiences, with some having side effects and others seeing positive results from the treatment.

community The Effects of the Potassium Channel Opener Minoxidil on Renal Electrolytes Transport in the Loop of Henle

in Minoxidil 8 upvotes 3 years ago

This post and conversation are about the effects of Minoxidil on renal electrolytes transport in the Loop of Henle. The replies show a lack of interest and a brief summary stating that rectal Minoxidil electrolytes are bad.

community Microneedling to maintain results from min

in Microneedling 7 upvotes 1 month ago

Microneedling alone is not effective in maintaining minoxidil results for hair growth. Combining microneedling with minoxidil and finasteride may enhance results, but microneedling by itself is not a reliable treatment.

community Minoxidil and Caffeine - opposite effects yet comboed together?

in Product 1 upvotes 2 months ago

Minoxidil and caffeine are discussed for hair loss treatment. The user questions the logic of combining them due to their opposing effects on adenosine receptors.

community A possible way to reap the benefits of finasteride with no risk of side effects

in Finasteride 15 upvotes 8 years ago

A user suggests that a .25% topical finasteride solution could reduce scalp DHT levels without affecting bloodstream DHT levels, potentially avoiding sexual side effects. They question why a 2.5% solution was chosen and if a custom .25% solution can be ordered.

community Sustaining minoxidil dependent hairs?

in Research/Science 9 upvotes 7 months ago

Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.