community Any bludfluw or placebo supplements to slow down graying?
The user has accepted their hair loss and uses finasteride and minoxidil, with past use of RU58841 and dutasteride. They seek advice on supplements to slow down graying hair.
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30 / 654 resultscommunity Caffeine really a DHT blocker or placebo?
Caffeine is not a proven DHT blocker and does not effectively treat hair loss. Minoxidil, finasteride, and RU58841 are more reliable treatments.
community Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial
Pumpkin seed oil may help hair growth in men with androgenetic alopecia. Treatments discussed include Minoxidil, finasteride, and RU58841.
community TDM-105795 phase 2 results are in!
TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
community Here's why Pryiltamide "failed" phase 3 trials and marketed as a cosmetic
KX-826 failed Phase III trials due to high placebo effects, patient compliance issues, COVID-19 side effects, and detection method deviations. KX-826 is now marketed as a cosmetic and approved for combination with Minoxidil.
community Pyrilutamide phase III clinical trial results released
Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.
community Why haven’t we seen anything about this
A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.
community Despite its straightforward mrchanism of action, it looks like pyrilitamide doesn't help regrow hair like finasteride does.
Pyrilitamide (KX-826) did not show significant improvement in hair count compared to placebo after 6 months. It's unclear if it can maintain hair at baseline.
community Setipiprant trial results
Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.
community Is there a consensus on RU these days? Pyril turned out to be a bust right?
The conversation discusses the effectiveness and safety of hair loss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.
community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide
Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.
community 35% regrowth brothers and sisters! More effective than Minox and Fin?
A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.
community Shouldn’t it be impossible for dutasteride to make hair loss worse?
Dutasteride is unlikely to worsen hair loss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.
community Breaking hair loss news! GT20029 is a resounding success!
GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.
community KX-826 Phase 3 Failed. Sorry guys...
The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.
community Lilly to seek first approval of an autoimmune drug for hair loss
Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.
community Saw palmetto sides are the same as finasteride? Im going to lose my time and money with "natural drugs"?
A 25-year-old is considering using saw palmetto for hair loss due to fear of finasteride side effects but is concerned about its effectiveness and cost compared to finasteride. They are seeking advice on whether saw palmetto has similar side effects to finasteride and if it's truly effective or just a placebo.
community Exercise seems to be helping, a lot, quickly.
Exercise may be improving hair thickness and reducing thinning for a 50-year-old man using topical finasteride, minoxidil, Nizoral, and microneedling. The improvement could be due to exercise, the treatments, or a placebo effect.
community Six weeks so far on oral fin / topical min. I'm not overthinking it but I think the crown's getting thicker.
A male in his 30s is using 1.25 mg finasteride daily, 5% minoxidil foam twice daily, collagen/biotin supplements, and weekly .5mm rolling. After six weeks, he notices his crown appears thicker and feels better, possibly due to placebo.
community Kintor Pharma Announces Successful Completion of Phase II Clinical Trial of KX-826 for Treatment of Androgenetic Alopecia in the US
Kintor Pharma announced successful Phase II trial results for KX-826 in treating hair loss, showing it's comparable to finasteride and can be used with it. Some participants saw a 10 hair/cm^2 increase, which is considered a good outcome at the low dose used.
community Take multivitamins if you have sexual side effects! it's amazing
A user shared that taking multivitamins, specifically Myprotein "Alpha Man," improved their sexual energy while on finasteride. They believe the benefits come from Zinc and Vitamin B6/12.
community Has pyrilutamide worked for anybody?
The post discusses the effectiveness of pyrilutamide for hair loss. The user maintains hair with alfatrodial, fluridil, minoxidil, and keto shampoo but is seeking a simpler and cheaper alternative.
community Average tressless user after taking oral minoxidil
The conversation is about hair loss and the use of minoxidil (Minoxidil) and finasteride (Fin) as treatments. The conclusion is that some users have seen success in maintaining their hair with minoxidil, but there are varying opinions on the effectiveness of the treatments.
community Saw palmetto, eucapil and micro needeling
User noticed receding temples, used minoxidil and microneedling with positive results. Added saw palmetto and eucapil, experienced shedding and thinner hairline, but no side effects.
community 19 y/o on finasteride. Side effects, mental health and physical health!
A 19-year-old has been using finasteride for 3 months to treat hair loss and is experiencing side effects like erectile dysfunction and dizziness. They plan to continue with a reduced dosage while monitoring their health and are seeking advice from others with similar experiences.
community Anagenic Pyrilutamid, has anyone tried this?
The conversation is about personal experiences with Anagenic Pyrilutamid for hair loss and what carriers people use with it. No specific treatments or outcomes are mentioned.
community Is it possible that dutasteride won’t make you depressedd if finasteride did?
The conversation discusses whether dutasteride might cause less depression than finasteride for hair loss treatment, with some users suggesting it could due to different mechanisms of action or molecular size, while others express skepticism or share personal experiences with these medications.
community Fin fuckbois to ascended masters
Hair loss treatments discussed include Minoxidil, Finasteride, microneedling, red light therapy, and biotin pills. The most proven treatments are Minoxidil, Finasteride, and microneedling, while other methods are considered less effective or satirical.
community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?
The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.
community Just quit nicotine and caffeine
The user has been using finasteride and oral minoxidil for hair loss but hasn't seen improvement and is quitting nicotine and caffeine to see if it helps. Some believe quitting nicotine improved their hair health due to better blood flow, while others are skeptical about the impact of blood flow on hair loss.