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    Glossary Patched 1

    Patched 1 (PTCH1) is a gene that encodes a protein involved in the Hedgehog signaling pathway, which plays a crucial role in regulating hair follicle development and cycling. Mutations or dysregulation of PTCH1 can lead to hair loss conditions, as it affects the proliferation and differentiation of hair follicle cells. Key distinguishing characteristics of PTCH1 include its involvement in both embryonic development and the maintenance of adult hair follicles, making it a significant factor in understanding hair biology and potential hair loss therapies.

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