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GlossaryP-cadherin

protein aiding cell adhesion in tissue structure maintenance

P-cadherin is a protein that helps cells stick together, playing a crucial role in maintaining the structure of tissues, including hair follicles. It is part of the cadherin family, which are important for cell adhesion, signaling, and maintaining the integrity of tissues. In the context of hair, abnormalities in P-cadherin expression can be linked to hair loss conditions like alopecia.

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community 2.5 months of oral minoxidil 5mg

in Progress Pictures 2 years ago

This conversation is about a user's progress with using oral minoxidil 5mg to treat their hair loss, in combination with finasteride. The replies discuss the effectiveness of this treatment and provide additional information on potential methods for obtaining it.

community On the topic of HMI-115 and prolactin: has anyone tried adding Vitamin B6 (P-5-P) to their topical solutions?

in Research/Science 7 upvotes 1 year ago

The conversation discusses the potential benefits of adding Vitamin B6 (P-5-P) to topical hair loss treatments like RU58841, finasteride, or minoxidil. The user suggests that Vitamin B6 might enhance these treatments by naturally lowering scalp prolactin.

community Any merit to this daily leave in foam? Saw P/Caffeine

in Treatment 2 upvotes 5 months ago

The conversation is about hair loss treatments. The user considers using a foam with Saw palmetto, caffeine, and EGCG, but another user suggests just using finasteride.

community Looking for Latanoprost sources EU

in Product 2 upvotes 1 year ago

The user has been using MinoxidilMax Latanoprost 0.01% and noticed an increase in hair density after years of stability on finasteride and minoxidil. They are seeking help to find a higher dosage of Latanoprost or a reliable source to purchase the powder to make their own, without a prescription or high cost.

community New study shows that microneedling is an ineffective hair loss treatment

in Research/Science 1 year ago

The effectiveness of microneedling as a hair loss treatment, with evidence from studies and anecdotal accounts from other users. It is suggested that combining microneedling with minoxidil or finasteride may be more effective than using microneedling alone, although some people have had success using only microneedling.

community My Hair Journey

in Journals / Progress Pictures 40 upvotes 3 days ago

The user takes 1mg of finasteride daily and applies Rogaine (minoxidil) twice a day. The first picture is from July 2023, and the last is from November 2024, showing hair progress.

community Using fin/min/dut and getting HT in December of 2024

in Journals / Progress Pictures 270 upvotes 4 weeks ago

The user is using finasteride, minoxidil, and dutasteride for hair loss, but stopped dutasteride due to side effects. They plan to have a hair transplant in December 2024 at Vanity Hospital in Istanbul, aiming for at least 4500 grafts.

community Nice progress after 4.5 months of 1 mg Fin and 5% Min - still wanting HT, I guess?

in Journals / Progress Pictures 128 upvotes 1 month ago

The user experienced significant hair regrowth and darkening after 4.5 months using 1 mg Finasteride and 5% Minoxidil. Despite improvements, they are still considering a hair transplant for a better hairline.

community “Progress” pictures. Should I just give up?

in Journals / Progress Pictures 237 upvotes 1 month ago

The user has been using Finasteride and Minoxidil for hair loss but has seen no progress. Suggestions include trying Dutasteride, increasing Minoxidil dosage, or considering a hair transplant.

community Ru-58841 vs KX-826/pyrilutamide while on steroids

in Finasteride/Dutasteride 3 upvotes 3 weeks ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

community [26M] 3.5 year update. Fin+Min

in Progress Pictures 3399 upvotes 5 months ago

A user shared their 3.5-year hair loss treatment journey using finasteride and minoxidil, showing significant hair density improvement and no noticeable side effects. The user also mentioned the confidence boost from shaving their head and the positive impact of the treatments.

community Topical Spironolactone 2.5% MONOTHERAPY x 1 year (MALE)- Nothing else

in Progress Pictures 8 upvotes 6 months ago

A male in his early 40s, who experienced side effects from finasteride, used 2.5% topical spironolactone for one year with no side effects but minimal regrowth. He plans to try a 5% spironolactone solution next.

community Wake up babe,the Lego microneedling set just dropped

in Satire 152 upvotes 9 months ago

The conversation is a humorous discussion about a Lego microneedling set for hair loss, comparing it to a wax pen. No specific treatments are mentioned.

community Topical Spironolactone 2.5% MONOTHERAPY x 5 months (MALE)- Nothing else

in Progress Pictures 15 upvotes 1 year ago

A man in his 40s treating his slow balding with a daily regimen of 2.5% spironolactone topical solution and Piroctone Olamine Shampoo. Despite initial hair shedding, he experienced no side effects and plans to continue the treatment for at least a year.

community 5 month results on natural protocol, i made a post after 3 mont of treatment wich you can find in my profile. I used different massages(detumescence therapy, wooden brush, tom hagerty exercises)vitamins(d3,fish oil, biotin,msm, magnesium) drank green tea and ate pumpkin seeds( reduces dht)

in Is this regrowth? 151 upvotes 1 year ago

The user "Zealousideal-Pack340" shared their 5-month results on a natural hair loss treatment protocol, which included massages, vitamins, green tea, and pumpkin seeds. Some users suggested using medications like finasteride and minoxidil for better results, while others criticized the effectiveness of natural remedies. Overall, there was no clear consensus on the progress of the user's hair regrowth.

community Study: Peppermint oil more effective than minoxidil, thoughts?

in Research/Science 14 upvotes 1 year ago

The conversation discusses a claim that peppermint oil is more effective than minoxidil for hair loss, with one user mentioning using a mix of peppermint and rosemary oils as a treatment. Some users are skeptical, while others show interest in the potential of peppermint oil.

community Are there any hair loss clinics in the U.S. that offer dutasteride mesotherapy?

in Finasteride/Dutasteride 6 upvotes 3 years ago

The conversation discusses the effectiveness of dutasteride injections for hair loss, often paired with oral minoxidil and oral finasteride/dutasteride. The user is seeking information on U.S. clinics offering this treatment.

community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?

in Research/Science 104 upvotes 4 years ago

Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.

community Should I Switch to Oral Minoxidil While Continuing Dutasteride? Need Advice on Next Steps After Accelerated Shedding

in General 159 upvotes 1 month ago

The user is experiencing increased hair shedding and is considering switching from a topical solution containing minoxidil, finasteride, and tretinoin to oral minoxidil while continuing oral dutasteride. They are seeking advice on whether to make this switch or wait for the shedding to stabilize, and are concerned about potential side effects of oral minoxidil.

community Can rosemary oil cause gynaecomastia?

in Microneedling 2 months ago

A user is concerned that using rosemary oil after microneedling might cause gynaecomastia due to increased absorption and potential DHT blocking. Other users believe rosemary oil is unlikely to affect hormones or cause gynaecomastia.

community The Empire (Itch) Strikes Back

in Is this regrowth? 5 upvotes 2 months ago

A 22-year-old male using 0.5mg Dutasteride and 2.5mg oral Minoxidil daily for 5.5 months reports increased shedding and scalp itching. He also experienced acne and is concerned about whether the shedding is normal and if daily hair washing for seborrheic dermatitis is causing dryness.

community 45 years old - 4 months topical fin / min

in Progress Pictures 114 upvotes 3 months ago

A 45-year-old user shared progress pictures after 4 months of using a topical gel with 2.5% finasteride and 5% minoxidil once daily. The second picture shows significant improvement in hair growth.

community No luck with meds, Check your Cortisol.

in Treatment 32 upvotes 3 months ago

Cortisol from stress can cause hair loss. Controlling cortisol levels improved the effectiveness of finasteride for hair regrowth.

community Hair Regrowth with Novel Hemp Extract - anyone seen this??

in Research/Science 18 upvotes 3 months ago

A user discusses a novel hemp extract for hair regrowth, which showed superior results to finasteride and minoxidil. The formula includes CBD, CBDV, THCV, delta 9 THC, cannabigerol, and cannabinol, combined with menthol, peppermint oil, ethanol, Emu oil, HFA 134A propellant, and dimethicone.

community How did you know I was balding?

in Satire 42 upvotes 4 months ago

The conversation humorously discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. The user jokes about the obvious signs of balding.

community To the late responders of finasteride. How long did it take to finally see results?

in Finasteride/Dutasteride 219 upvotes 5 months ago

Finasteride can take over a year to show results, with some users seeing significant improvements after 1.5 to 3.5 years. Patience is key, and combining treatments like minoxidil may help.

community Countering oral minoxidil side effects by taking collagen supplements?

in Minoxidil 16 upvotes 5 months ago

Oral minoxidil may deplete collagen, potentially causing skin aging. Users discuss whether taking collagen supplements can counteract this effect.

community Latanoprost from the gray market?

in Chat 4 upvotes 5 months ago

The conversation discusses sourcing pure latanoprost from the gray market for research and making a homemade solution. Concerns about potential dangers and experiences with this method are raised.

community "When comparing 5% minoxidil with 0.60 mm or 1.20 mm needle lengths, Faghihi et al. found that 0.60 mm needle lengths led to significant hair count and diameter increases versus 5% minoxidil, whereas 1.20 mm needle lengths only saw hair count increases versus 5% minoxidil"

in Research/Science 60 upvotes 5 months ago

Microneedling with 0.6 mm needles combined with 5% minoxidil is more effective for hair count and thickness than minoxidil alone or with 1.2 mm needles. Biweekly microneedling at 0.6 mm depth is recommended for better results in treating androgenetic alopecia.

community Rosemary oil as a growth agonist instead of min

in Chat 1 upvotes 6 months ago

The user uses finasteride, ketoconazole shampoo, and derma stamping for hair loss. They consider rosemary and castor oil as alternatives to minoxidil due to fewer side effects.