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GlossaryOff-label Use

Off-label use refers to the practice of prescribing a medication for a purpose that has not been officially approved by regulatory agencies like the FDA. This can include using the drug to treat a different condition, in a different dosage, or in a different patient population than what is specified in the approved labeling. While off-label use is legal and can be based on sound medical evidence, it often requires careful consideration and professional judgment.

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community Men on here: did you have trouble getting a derm to prescribe you “off label” meds?

in Chat 3 upvotes 4 months ago

A woman with androgenic alopecia has been using birth control, spironolactone, finasteride, and oral minoxidil for hair loss. She sought to change her medications to dutasteride and bicalutamide, but her new dermatologist refused to prescribe them for off-label use.

community Would you still need to be on finasteride if Verteporfin becomes widely used?

in Research/Science 24 upvotes 9 months ago

The conversation discusses whether finasteride would still be necessary if Verteporfin becomes a successful hair loss treatment. It also explores the sensitivity of transplanted hair to DHT and the potential for off-label use of Verteporfin post hair transplant.

community No, Finasteride as a treatment for MPB was not an "accident"

in Research/Science 105 upvotes 3 years ago

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

community New Latanoprost-Based Formula Used by Hollywood Celebrities

in Treatment 27 upvotes 1 year ago

A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

community The Oral Minoxidil hype, use your head .

in Minoxidil 10 upvotes 1 year ago

The conversation is about the risks and uncertainties of using oral Minoxidil for hair loss, emphasizing that topical Minoxidil may be just as effective. It also mentions alternative treatments like micro-needling and retinol.

community Crown Progress - 3 Months Min & 3 weeks Finasteride Progress

in Progress Pictures 72 upvotes 8 months ago

The user shared their hair regrowth progress after a hair transplant and using Minoxidil (Regaine Foam) and Finasteride, hoping to regrow their crown. They started Minoxidil in September and Finasteride in November, and have noticed increased hair density.

community Which retinoid for better min absorption?

in Product 4 upvotes 2 days ago

User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.

community Bad experience at Dermatologist

in Update 42 upvotes 2 years ago

A user had a disappointing dermatologist appointment where they were denied prescriptions for Dutasteride and oral Minoxidil for hair loss and were only offered a hair transplant referral. Other users sympathized, discussed self-medication, and suggested consulting a transplant doctor for up-to-date treatments.

community 4 months worth of progress! Seeing some results!

in Progress Pictures 60 upvotes 1 month ago

User shared 4 months of hair loss progress using finasteride and minoxidil, noting improved scalp health with the right shampoo. Encouragement from others includes success stories with similar treatments.

community What’s your experience with RU58841?

in Treatment 21 upvotes 1 year ago

People shared mixed experiences with RU58841 for hair loss; one person saw no improvement, another had significant gains and uses it with finasteride, while a third had an allergic reaction to the premixed solution. Some mix RU58841 powder into minoxidil themselves.

community Progress pics march 2022 vs june 2023, 7 months dutasteride after only maintaining on fin for 6 months.

in Progress Pictures 37 upvotes 1 year ago

User maintained hair with finasteride for 6 months, then switched to dutasteride for 7 months, using DHT blocking shampoo, keto 2% shampoo, and microneedling. Significant hair growth observed, especially on right temple.

community 4 months min 2x daily fin 1x feeling reallll good about it

in Progress Pictures 336 upvotes 1 year ago

A user's progress with treating their hair loss by using Minoxidil twice daily and finasteride once daily, as well as suggestions to add microneedling and avoid tying the hair back.

community switched from topical to oral minoxidil (topical mixed with water) 3 months ago and aside from being much easier i’ve also had much more density overall. My results aren’t even finished yet!

in Progress Pictures 1 year ago

This user discussed using oral minoxidil as a hair loss treatment, and was cautioned against mixing topical minoxidil with water and drinking it due to potential side effects and risks. Other users shared their concerns about the dangers of self-prescribing medications without consulting a doctor.

community Thinking about my making own CB-03-01 (Breezula). Thoughts?

in Treatment 7 upvotes 3 years ago

The user experienced side effects with both oral and topical finasteride and is considering making their own hair loss treatment using CB-03-01 (Breezula) mixed with minoxidil due to fewer reported side effects. They plan to use a lower concentration than what was used in trials.

community Some more realistic 15 months fin+min results. No loss, but also basically no growth. HT unfortunately seems like the only option left at this point :/

in Progress Pictures 114 upvotes 2 months ago

User shared 15-month results using finasteride and minoxidil, showing no loss but minimal growth, considering a hair transplant. Replies suggest starting treatment earlier, continuing current treatment, or getting a transplant.

community 25 months. Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL, fixing vitamin D levels

in Progress Pictures 2247 upvotes 3 years ago

User "manlycoffee" shares 25-month progress using Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL, and fixing vitamin D levels for hair loss. Users discuss sources, experiences, and side effects of treatments.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 119 upvotes 6 months ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community Dermatologist denied prescribing oral dutasteride because it’s not FDA approved BUT did prescribe ORAL minoxidil 😂

in Finasteride/Dutasteride 31 upvotes 1 month ago

A 22-year-old male has been using oral finasteride for a year with no improvement in hair loss and was denied dutasteride by a dermatologist due to FDA approval issues but was prescribed oral minoxidil instead. The user is seeking advice on whether to switch to dutasteride, continue finasteride, or add minoxidil.

community Just under 3 mos of topical min/fin 1x/daily, 0.5mm dermarolling daily (before application), and 2% ketoconazole shampoo 3x/week

in Progress Pictures 72 upvotes 6 months ago

The conversation discusses hair loss treatment using daily topical minoxidil and finasteride, daily 0.5mm dermarolling before application, and 2% ketoconazole shampoo three times a week. Users believe dermarolling enhances the absorption of the treatments and expect significant improvements over time.

community Kintor develop GT20026 Anti-Androgen receptor drug with NO SIDES

in Treatment 17 upvotes 3 years ago

The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.

community Fevipiprant 2019!

17 upvotes 7 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community Guide: How to EASILY get prescription oral minoxidil

in Minoxidil 19 upvotes 2 years ago

The conversation provides a six-step guide on how to get a prescription for oral minoxidil (OM) for hair loss by finding a supportive dermatologist, even if they are not local, and preparing a case for its use during a virtual consultation. The guide emphasizes the importance of research, insurance considerations, and the potential for initial hair shedding with OM treatment.

community Only 10 more days until cassiopea releases their 12 month results for CB-03-01 our best hope of an alternative to finasteride

in Finasteride 150 upvotes 5 years ago

The conversation discusses anticipation for CB-03-01, a potential new hair loss treatment that may be more effective and have a cleaner safety profile than finasteride. Users are hopeful but cautious, discussing current treatments like minoxidil, nizoral, and dermarolling, and the possibility of combining them with CB-03-01 for better results.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 1 year ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community "Finasteride Lore: Reversing Hair Loss Takes Years. Not Months." for all the people who worry about results after 3 months on Finasteride, or even worse stop taking it becuase "it wasn't working for me

in Finasteride/Dutasteride 136 upvotes 1 month ago

Finasteride can take years to show results, not months. Dutasteride may work faster but is less commonly prescribed.

community Dr. Gabel Doesn't Use Verteporfin

in Transplants 5 upvotes 3 days ago

Dr. Gabel doesn't use Verteporfin because it's not FDA approved. The user is getting FUT and wants to minimize scarring and maximize hair regrowth.

community 12 mo update: oral (dut, min), topical (RU, min), microneedling

in Progress Pictures 354 upvotes 1 year ago

A user's 12 month update on treatment for hair loss, which include oral dutasteride and minoxidil, topical RU88541 and minoxidil, microneedling with hyaluronic acid and FinDuta, experiencing no side effects, positive results and inspiring other users.

community 2 months results: Dut 0.5mg / Oral min 2.5mg / Dut+PRP mesotherapy / microneedling

in Progress Pictures 85 upvotes 1 year ago

User's 2-month hair loss treatment includes Dut 0.5mg, oral min 2.5mg, Dut+PRP mesotherapy, microneedling, and other products. Dermatologist increased min dose to 5mg, expecting better results at 6-month mark.

community 1 year on fin. No results. I give up.

in Finasteride/Dutasteride 1 year ago

A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.