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Glossary Nicotine

highly addictive stimulant found in tobacco plants

Nicotine is a highly addictive chemical compound found in tobacco plants. It acts as a stimulant in small doses, increasing heart rate and alertness, but can be toxic in larger amounts. Nicotine binds to nicotinic acetylcholine receptors in the brain, leading to the release of neurotransmitters like dopamine, which contributes to its addictive properties.

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community Nicotine and shedding; does it make hair loss worse ?

4 upvotes 1 week ago

Nicotine use appears to increase hair shedding, with users noticing more hair loss when using nicotine and less when abstaining. Some users plan to quit nicotine and start treatments like finasteride and oral minoxidil to improve hair quality.

community Does nicotine have an effect on hair despite using finasteride?

in Research/Science 11 upvotes 5 months ago

Nicotine may negatively affect hair by reducing blood flow due to its vasoconstrictor properties, but its impact might be minimal. Finasteride users are advised to avoid nicotine to prevent potential hair loss issues.

community People who continue to lose hair on fin/dut, Are you on Nicotine?

in Research/Science 81 upvotes 1 year ago

Nicotine use, especially from vaping, may worsen hair shedding and reduce the effectiveness of finasteride and dutasteride. Quitting nicotine seems to improve hair health.

community Has anyone tried nicotinamide serum for inflammatory hair loss.

3 upvotes 1 year ago

Nicotinamide serum is discussed for its potential benefits in reducing inflammation related to hair loss. One user combines it with minoxidil for hair growth.

community Oral Supplementation of Nicotinamide Mononucleotide (NMN) Improves Hair Quality and Subjective Perception of Hair Appearance in Middle-Aged Women

2 upvotes 11 months ago

Oral supplementation of Nicotinamide Mononucleotide (NMN) improves hair quality and appearance in middle-aged women. However, it may reduce total hair density, possibly due to seasonal shedding.

community guys can we consume NMN(Nicotinamide mononucleotide) while being on dutasteride?

1 upvotes 1 year ago

NMN is considered safe to use with dutasteride, and it may help reduce grey hairs. Combining NMN with creatine, whey protein, fish oil, and dutasteride is not seen as excessive.

community 1 month and 1 week: 1mg Finasteride daily, 5% topical Minoxidil once or twice a day, 4000 IU of Vitamin D, and cutting out nicotine

in Is this regrowth? 6 upvotes 1 year ago

Hair appears to be improving with a regimen of 1mg Finasteride daily, 5% topical Minoxidil once or twice a day, 4000 IU of Vitamin D, and cutting out nicotine. It's still early to determine the full effect.

community Is it just miniaturized or will I need some grafts in here?

in Treatment 8 upvotes 1 month ago

The user is experiencing hair loss despite using finasteride and oral minoxidil, and is considering a hair transplant due to limited regrowth. Suggestions include trying stronger treatments like dutasteride and RU58841, quitting nicotine, and maintaining a healthy lifestyle.

community Sudden dutasteride and OM shed after 1.5 yrs

33 upvotes 3 weeks ago

The user experienced significant hair shedding after 1.5 years on dutasteride and oral minoxidil, possibly due to a shedding cycle or lifestyle changes like nicotine use and creatine. Opinions vary on whether creatine contributes to hair loss, with some attributing shedding to synchronized hair cycles or genetic factors.

community Progress photos 1month-3month comparison read description

in Progress Pictures 2 upvotes 4 months ago

The user experienced significant hair regrowth after starting treatment with 1.2mg finasteride and 5mg minoxidil in January 2026. They also reduced stress and stopped drug use, except for nicotine, which contributed to their progress.

community 10 months progression (plz respond)

4 upvotes 5 months ago

The user is experiencing hair shedding after using minoxidil and is considering switching to dutasteride while planning to increase their oral minoxidil dose. They also use nicotine pouches, Vyvanse, and GHK-Cu, and have noticed thicker eyebrows and lashes from oral minoxidil.

community Day 1 vs 1 month vs 4 months vs 6 months vs 1 year vs 1 year 3 months (My story)

in Progress Pictures 109 upvotes 6 months ago

A 23-year-old experienced hair regrowth using 1mg finasteride and 5mg oral minoxidil after initial shedding, but noticed hair loss after stopping minoxidil and starting vaping. They resumed oral minoxidil and finasteride, attributing hair loss to nicotine and stopping minoxidil, and are considering additional treatments like dutasteride.

community 10months on minoxidil as an “ok responder”

in Progress Pictures 205 upvotes 1 year ago

The user added topical minoxidil to their finasteride regimen, resulting in healthier hair and some regrowth, especially after quitting nicotine. They experienced minimal shedding and noted improvements in hairline density, finding the treatment mostly preventative.

community Fin/min Progress April - December 2024

in Progress Pictures 255 upvotes 1 year ago

The user experienced significant hair regrowth using 1mg finasteride daily and Rogaine minoxidil 5% foam twice a day, along with vitamin D supplementation. They also managed stress through lifestyle changes like exercise, quitting nicotine, and improving sleep.

community Need help bros 2.5mg Dut/RU/min ISNT enough

in Finasteride/Dutasteride 2 years ago

A user is experiencing worsening hair loss despite using 2.5mg Dutasteride, RU58841, and Minoxidil daily for over 8 months. They are concerned that daily nicotine from vaping might be counteracting the treatments.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 2 years ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Starting a new treatment regimen tomorrow!

4 upvotes 4 years ago

The user started a new hair loss treatment regimen using topical finasteride and minoxidil, saw palmetto, sulforaphane, and apple extract supplements, while also trying to quit nicotine and fast food. They later cut out supplements due to cost, continued with topical treatment, and experienced improved hair health but faced issues with low libido.

community My HT experience: I ALMOST FAINTED, excessive bleeding, scary moment post-op, and density anxiety at week 3

in Progress Pictures 13 upvotes 8 months ago

A person shared their hair transplant experience, mentioning complications like excessive bleeding and density anxiety, and is using finasteride and minoxidil chewables. They traveled to Turkey for the procedure, paid around $3800, and are considering Mexico for future treatments; nicotine use is a concern for their recovery.

community Help me figure out the confusing difference between regrowth and hair loss indicators

in Is this regrowth? 1 upvotes 10 months ago

The user is seeking opinions on whether their hairline changes indicate regrowth or hair loss, using treatments like Rogaine, finasteride, microneedling, and Nizoral. They mention inconsistent finasteride use, scalp massages, and lifestyle factors like caffeine, nicotine, stress, and high sugar intake.

community NMN supplementation experiences?

2 upvotes 8 months ago

The conversation discusses experiences with NMN supplementation for hair growth, with some users reporting increased hair growth activity and others seeing no significant changes. OP has been using dutasteride and oral minoxidil, and recently added NMN, noticing increased shedding, which they hope indicates new hair growth.

community Has anyone’s hair improved/saw more regrowth/thickening after quitting smoking cigarettes.

12 upvotes 2 months ago

Quitting smoking may improve hair quality and overall health, but it is not a standalone solution for reversing hair loss. Treatments like finasteride and minoxidil are more effective for hair regrowth, while smoking can exacerbate hair loss by increasing DHT and affecting scalp health.

community Approve PP405 quickly you coward

in Satire 193 upvotes 1 year ago

Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

community Had to quit minoxidil because of headaches

15 upvotes 2 years ago

The user stopped using minoxidil due to headaches, which returned upon resuming the treatment, leading to hair shedding concerns. Alternatives like finasteride and diluted minoxidil were suggested by others experiencing similar side effects.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Chad to Chud : Or How I Undid My Hairloss

246 upvotes 1 month ago

The user shared their hair loss recovery journey using minoxidil, finasteride, topical rogaine, microneedling, biotin shampoo, and lifestyle changes like quitting smoking and improving diet. They emphasized the importance of daily choices in addition to treatments for hair health.

community [M24] Do you think it's working ?

3 upvotes 5 months ago

A 24-year-old male is using topical Minoxidil and Finasteride, along with microneedling, to address hair loss and is seeing some improvement, though it's early in the treatment process. The user is advised to continue the regimen for at least 12 months for a clearer assessment, with some recovery possibly due to resolving telogen effluvium from a previous caloric deficit.

community Alvi Armani Dr Craig Barton review salt lake city utah

in Transplants 169 upvotes 7 months ago

A user shared their positive experience with hair transplants by Dr. Craig Barton, having undergone two surgeries totaling 3,600 grafts for $12,000. They have been using finasteride and dutasteride for maintenance but stopped using minoxidil due to shedding issues.

community 13 months TOPICAL ONLY progress! (Diffuse thinner)

554 upvotes 9 months ago

The conversation is about a user's progress in treating diffuse hair thinning using a topical regimen including finasteride, minoxidil, ketoconazole, microneedling, saw palmetto, collagen, and vitamins, along with lifestyle changes. The user plans to switch from topical to oral finasteride for potentially better results.

community 4 months of progress, lots of new terminal hairs, diffuse thinning. 31m

10 upvotes 11 months ago

A 31-year-old man shares his 4-month hair regrowth progress using topical minoxidil, topical finasteride, microneedling, biotin, and other supplements. He reports new hair growth despite experiencing side effects from finasteride and plans to continue his regimen for further improvement.

community Scalp inflammation let’s talk about it?

in Chat 11 upvotes 1 year ago

Scalp inflammation can cause hair thinning and may be related to diet, infections, or conditions like psoriasis. Treatments suggested include using Nizoral shampoo and checking vitamin levels.