Search

for
Search:

GlossaryNF-κB activation

process where a protein complex moves to the nucleus

NF-κB activation refers to the process by which the NF-κB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) protein complex is triggered to move from the cytoplasm into the nucleus of a cell. Once in the nucleus, it binds to DNA and activates the transcription of specific genes involved in immune and inflammatory responses, cell growth, and survival. This pathway is crucial in many biological processes and is often implicated in diseases such as cancer and autoimmune disorders.

Related Terms

Sort by

Community Join

6 / 6 results

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 444 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Topical Finasteride update by H&W

in Finasteride 28 upvotes 7 years ago

The conversation discusses using topical finasteride for hair loss, with concerns about its safety around family members, especially pregnant women and infants. One user plans to try topical finasteride due to side effects from the pill.

community Finasteride + Minoxidil + Ketozolin Shampoo + Vitamin D and Biotin results

in Progress Pictures 320 upvotes 2 years ago

So maybe vitamin D is important here This conversation discussed the user's successful results from a combination of treatments, including finasteride, minoxidil, ketozolin shampoo, Vitamin D and biotin. The discussion also included advice about frequency and dosages for these treatments.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 121 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.