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Did you mean Melatonin Receptor 2?

GlossaryMelatonin Receptor 2

protein that binds melatonin to regulate sleep-wake cycles

Melatonin Receptor 2 (MT2) is a protein found in the body that binds to melatonin, a hormone that regulates sleep-wake cycles. This receptor plays a crucial role in various physiological processes, including circadian rhythm regulation and potentially influencing mood and immune function. Understanding MT2 is important for developing treatments for sleep disorders and other conditions related to the body's internal clock.

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community Hair loss causes are still a myth.

dannxFox in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

Additional_Rough_968 in Research/Science 47 upvotes 2 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Next month marks 2 years on Dutasteride. When does it start working?

Foreign_Fondant_2880 in Finasteride/Dutasteride 36 upvotes 8 months ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

EgyptStar81 in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community Perez Hilton Had 3 Transplants.. Yet Losing Hair.. Someone Explain?

ihwpa in Transplants 71 upvotes 1 year ago

The conversation discusses Perez Hilton's hair loss despite having three hair transplants. Participants suggest that hair loss can continue after a transplant if maintenance treatments like finasteride and minoxidil are not used, and that transplanted hair can still be susceptible to loss.

community Have you guys heard about topical melatonin?

Dispiteous in Research 10 upvotes 5 years ago

Topical melatonin may improve hair density and thickness, and reduce hair loss and seborrhea with no significant side effects. The user made their own melatonin solution for hair treatment.

community Melatonin a possible tool to help fight AGA hair loss.

treesgomeow in Research/Science 54 upvotes 3 years ago

Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

community CB-03-01 supposed hair loss cure

Intrepid-Soil817 in Treatment 9 upvotes 3 years ago

The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

community Has anyone ever tried using (all topicals) finasteride + minoxidil + rosemary oil + castor oil + stemoxydine all over the course of a few months/years?

lkkac in Treatment 3 upvotes 10 months ago

The user is using topical finasteride and minoxidil for hair loss and is considering adding rosemary oil, castor oil, and stemoxydine to their routine. They are asking if anyone has experience with this combination or a similar one.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

Combfromhell in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community 1 month Pyrilutamide. A non responders story to everything.

Combfromhell in Research/Science 218 upvotes 2 years ago

My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

community How would you start your hairloss battle if you were 16 y.o?

bossver in Treatment 15 upvotes 1 year ago

A 16-year-old experiencing hair loss seeks treatment advice. They decide to start with Serioxyl, Ketoconazole shampoo, and Eucapil, considering Minoxidil and Finasteride for later use.

community hmi115 is coming. Prepare yourselves for what's coming

HMI115_GIGACHAD in Technology 106 upvotes 1 year ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community The Golden Hair Regrowth/Loss Prevention Regimen With Results and Explanation

CumShotDiva in Treatment 227 upvotes 2 years ago

Hair loss prevention and regrowth regimen includes finasteride, oral minoxidil, stemoxydine, hair growth serum, derma rolling, and ketocanazole shampoo. Users discuss efficacy, safety, and personal experiences with treatments.

community Just started my journey, wish me luck

din_jarin7 in Product 96 upvotes 2 years ago

A user's journey to treat hair loss with a combination of oral medication, topical treatments, microneedling and different shampoos and supplements. It includes warnings about an OGX biotin shampoo potentially causing further hair loss.

community Why is dht bad for scalp hair but good for hair on the rest of body?

What_is_69 in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community Rosemary oil, peppermint oil, mucuna pruriens - two weeks in

tired45453 in Treatment 81 upvotes 1 year ago

A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hair loss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.

community People need to start accepting that only medical therapy (Fin/Dut) can save your hair in the long run.

Mirrormaster85 in Treatment 112 upvotes 1 year ago

Minoxidil can regrow hair but doesn't address the underlying issue of DHT, leading to continued hair loss. Users discuss their experiences with finasteride and dutasteride, mentioning side effects, personal outcomes, and alternatives like microdosing topical finasteride.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

Combfromhell in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

MagicBold in Research/Science 2 upvotes 2 months ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community What else is good. Besides the big 3.

Ill-Passenger-2468 in Chat 34 upvotes 4 months ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Last resort attempt. Studies suggest that finasteride topically actually inhibits up to 52% scalp dht which is smiles to dut 0.5mg daily. This solution contains: fin, min, melatonin and progesterone. Trial started today.

Combfromhell in Research/Science 8 upvotes 2 years ago

The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.

community What other factors than DHT causes hair loss – and what to do about it?

domsolanke in Treatment 2 years ago

Factors that can cause hair loss other than DHT, such as inflammation and diet, and potential treatments like scalp massages, minoxidil, citrulline, stretches, meditation, iron sulfate/Vitamin C, Vitamin D, protein and Dutasteride.

community 26, i was cool w shaving bald but I wanted to hold on for a little longer. Just topical min and rosemary shampoo.

DrGinkgo in Progress Pictures 688 upvotes 1 year ago

The post and conversation are about a user's successful regrowth of hair using topical minoxidil and rosemary shampoo. Other users discuss the potential limitations of minoxidil and recommend using finasteride to maintain hair growth.

community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?

MediumAcanthaceae486 in Technology 109 upvotes 1 year ago

The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.

community Will my liver get destroyed long term on this stack ??

ImpossibleWeakness67 in Chat 15 upvotes 11 months ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

community My nuclear protocol (scary but very effective)

hdvdrgsegxdr in Treatment 80 upvotes 2 years ago

A hair loss treatment protocol involving topical and oral medications such as Minoxidil, RU58841, Finasteride, Dutasteride, Melatonin, Zinc, Vitamin B6, NAC, Caffeine, Biotin, Ginseng, and Semen; other treatments including Microneedling, Laser Helmet, Nizoral shampoo, Scalp Massage and supplements like Vitamin C, Vitamin D, Fish Oil, and Biotin; and the potential side effects of using this protocol.

community Big increase in miniaturization after being on finasteride for 7 years?

throwaway83927493 in Finasteride/Dutasteride 29 upvotes 1 month ago

The user experienced increased hair miniaturization and shedding despite using finasteride, topical minoxidil, microneedling, and other treatments. They are considering more aggressive treatments or a hair system if no improvement occurs by the end of 2025.

community C’est terrible - at my wits end

Desperate-War-3925 in Female 447 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Topical quercetin combined with finasteride for max results

LITUATUI in Research/Science 25 upvotes 1 year ago

Combining Finasteride with topical Quercetin, Onion/Garlic juice and Peppermint Oil to reduce Wet Prostate Weight in Rats. Luke10191 asked the user LITUATUI to update them on progress after trying this combination of treatments for hair loss.